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Acute Kidney Injury in Severe COVID-19 Has Similarities to Sepsis-Associated Kidney Injury: A Multi-Omics Study.
Alexander MP, Mangalaparthi KK, Madugundu AK, Moyer AM, Adam BA, Mengel M, Singh S, Herrmann SM, Rule AD, Cheek EH, Herrera Hernandez LP, Graham RP, Aleksandar D, Aubry MC, Roden AC, Hagen CE, Quinton RA, Bois MC, Lin PT, Maleszewski JJ, Cornell LD, Sethi S, Pavelko KD, Charlesworth J, Narasimhan R, Larsen CP, Rizza SA, Nasr SH, Grande JP, McKee TD, Badley AD, Pandey A, Taner T. Alexander MP, et al. Among authors: mckee td. Mayo Clin Proc. 2021 Oct;96(10):2561-2575. doi: 10.1016/j.mayocp.2021.07.001. Epub 2021 Jul 15. Mayo Clin Proc. 2021. PMID: 34425963 Free PMC article.
Molecular, Metabolic, and Subcellular Mapping of the Tumor Immune Microenvironment via 3D Targeted and Non-Targeted Multiplex Multi-Omics Analyses.
Ferri-Borgogno S, Burks JK, Seeley EH, McKee TD, Stolley DL, Basi AV, Gomez JA, Gamal BT, Ayyadhury S, Lawson BC, Yates MS, Birrer MJ, Lu KH, Mok SC. Ferri-Borgogno S, et al. Among authors: mckee td. Cancers (Basel). 2024 Feb 20;16(5):846. doi: 10.3390/cancers16050846. Cancers (Basel). 2024. PMID: 38473208 Free PMC article.
Prkar1a is an osteosarcoma tumor suppressor that defines a molecular subclass in mice.
Molyneux SD, Di Grappa MA, Beristain AG, McKee TD, Wai DH, Paderova J, Kashyap M, Hu P, Maiuri T, Narala SR, Stambolic V, Squire J, Penninger J, Sanchez O, Triche TJ, Wood GA, Kirschner LS, Khokha R. Molyneux SD, et al. Among authors: mckee td. J Clin Invest. 2010 Sep;120(9):3310-25. doi: 10.1172/JCI42391. Epub 2010 Aug 9. J Clin Invest. 2010. PMID: 20697156 Free PMC article.
RANKL blockade prevents and treats aggressive osteosarcomas.
Chen Y, Di Grappa MA, Molyneux SD, McKee TD, Waterhouse P, Penninger JM, Khokha R. Chen Y, et al. Among authors: mckee td. Sci Transl Med. 2015 Dec 9;7(317):317ra197. doi: 10.1126/scitranslmed.aad0295. Sci Transl Med. 2015. PMID: 26659571
A Progesterone-CXCR4 Axis Controls Mammary Progenitor Cell Fate in the Adult Gland.
Shiah YJ, Tharmapalan P, Casey AE, Joshi PA, McKee TD, Jackson HW, Beristain AG, Chan-Seng-Yue MA, Bader GD, Lydon JP, Waterhouse PD, Boutros PC, Khokha R. Shiah YJ, et al. Among authors: mckee td. Stem Cell Reports. 2015 Mar 10;4(3):313-322. doi: 10.1016/j.stemcr.2015.01.011. Epub 2015 Feb 19. Stem Cell Reports. 2015. PMID: 28447939 Free PMC article.
Mice with tissue inhibitor of metalloproteinases 4 (Timp4) deletion succumb to induced myocardial infarction but not to cardiac pressure overload.
Koskivirta I, Kassiri Z, Rahkonen O, Kiviranta R, Oudit GY, McKee TD, Kytö V, Saraste A, Jokinen E, Liu PP, Vuorio E, Khokha R. Koskivirta I, et al. Among authors: mckee td. J Biol Chem. 2010 Aug 6;285(32):24487-93. doi: 10.1074/jbc.M110.136820. Epub 2010 Jun 1. J Biol Chem. 2010. PMID: 20516072 Free PMC article.
Resistance to dual blockade of the kinases PI3K and mTOR in KRAS-mutant colorectal cancer models results in combined sensitivity to inhibition of the receptor tyrosine kinase EGFR.
Belmont PJ, Jiang P, McKee TD, Xie T, Isaacson J, Baryla NE, Roper J, Sinnamon MJ, Lee NV, Kan JL, Guicherit O, Wouters BG, O'Brien CA, Shields D, Olson P, VanArsdale T, Weinrich SL, Rejto P, Christensen JG, Fantin VR, Hung KE, Martin ES. Belmont PJ, et al. Among authors: mckee td. Sci Signal. 2014 Nov 11;7(351):ra107. doi: 10.1126/scisignal.2005516. Sci Signal. 2014. PMID: 25389372
73 results