Gradinaru V - Search Results

1

Improved systemic AAV gene therapy with a neurotrophic capsid in Niemann-Pick disease type C1 mice.

Davidson CD, Gibson AL, Gu T, Baxter LL, Deverman BE, Beadle K, Incao AA, Rodriguez-Gil JL, Fujiwara H, Jiang X, Chandler RJ, Ory DS, Gradinaru V, Venditti CP, Pavan WJ. Davidson CD, et al. Among authors: gradinaru v. Life Sci Alliance. 2021 Aug 18;4(10):e202101040. doi: 10.26508/lsa.202101040. Print 2021 Oct. Life Sci Alliance. 2021. PMID: 34407999 Free PMC article.

2

Single-cell phenotyping within transparent intact tissue through whole-body clearing.

Yang B, Treweek JB, Kulkarni RP, Deverman BE, Chen CK, Lubeck E, Shah S, Cai L, Gradinaru V. Yang B, et al. Among authors: gradinaru v. Cell. 2014 Aug 14;158(4):945-958. doi: 10.1016/j.cell.2014.07.017. Epub 2014 Jul 31. Cell. 2014. PMID: 25088144 Free PMC article.

3

Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotyping.

Treweek JB, Chan KY, Flytzanis NC, Yang B, Deverman BE, Greenbaum A, Lignell A, Xiao C, Cai L, Ladinsky MS, Bjorkman PJ, Fowlkes CC, Gradinaru V. Treweek JB, et al. Among authors: gradinaru v. Nat Protoc. 2015 Nov;10(11):1860-1896. doi: 10.1038/nprot.2015.122. Epub 2015 Oct 22. Nat Protoc. 2015. PMID: 26492141 Free PMC article.

4

Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain.

Deverman BE, Pravdo PL, Simpson BP, Kumar SR, Chan KY, Banerjee A, Wu WL, Yang B, Huber N, Pasca SP, Gradinaru V. Deverman BE, et al. Among authors: gradinaru v. Nat Biotechnol. 2016 Feb;34(2):204-9. doi: 10.1038/nbt.3440. Epub 2016 Feb 1. Nat Biotechnol. 2016. PMID: 26829320 Free PMC article.

5

Global Representations of Goal-Directed Behavior in Distinct Cell Types of Mouse Neocortex.

Allen WE, Kauvar IV, Chen MZ, Richman EB, Yang SJ, Chan K, Gradinaru V, Deverman BE, Luo L, Deisseroth K. Allen WE, et al. Among authors: gradinaru v. Neuron. 2017 May 17;94(4):891-907.e6. doi: 10.1016/j.neuron.2017.04.017. Neuron. 2017. PMID: 28521139 Free PMC article.

6

Engineered AAVs for efficient noninvasive gene delivery to the central and peripheral nervous systems.

Chan KY, Jang MJ, Yoo BB, Greenbaum A, Ravi N, Wu WL, Sánchez-Guardado L, Lois C, Mazmanian SK, Deverman BE, Gradinaru V. Chan KY, et al. Among authors: gradinaru v. Nat Neurosci. 2017 Aug;20(8):1172-1179. doi: 10.1038/nn.4593. Epub 2017 Jun 26. Nat Neurosci. 2017. PMID: 28671695 Free PMC article.

7

Viral Strategies for Targeting the Central and Peripheral Nervous Systems.

Bedbrook CN, Deverman BE, Gradinaru V. Bedbrook CN, et al. Among authors: gradinaru v. Annu Rev Neurosci. 2018 Jul 8;41:323-348. doi: 10.1146/annurev-neuro-080317-062048. Epub 2018 Apr 25. Annu Rev Neurosci. 2018. PMID: 29709207 Review.

8

The Neuropeptide Tac2 Controls a Distributed Brain State Induced by Chronic Social Isolation Stress.

Zelikowsky M, Hui M, Karigo T, Choe A, Yang B, Blanco MR, Beadle K, Gradinaru V, Deverman BE, Anderson DJ. Zelikowsky M, et al. Among authors: gradinaru v. Cell. 2018 May 17;173(5):1265-1279.e19. doi: 10.1016/j.cell.2018.03.037. Cell. 2018. PMID: 29775595 Free PMC article.

9

Systemic AAV vectors for widespread and targeted gene delivery in rodents.

Challis RC, Ravindra Kumar S, Chan KY, Challis C, Beadle K, Jang MJ, Kim HM, Rajendran PS, Tompkins JD, Shivkumar K, Deverman BE, Gradinaru V. Challis RC, et al. Among authors: gradinaru v. Nat Protoc. 2019 Feb;14(2):379-414. doi: 10.1038/s41596-018-0097-3. Nat Protoc. 2019. PMID: 30626963

10

TRIM9-Mediated Resolution of Neuroinflammation Confers Neuroprotection upon Ischemic Stroke in Mice.

Zeng J, Wang Y, Luo Z, Chang LC, Yoo JS, Yan H, Choi Y, Xie X, Deverman BE, Gradinaru V, Gupton SL, Zlokovic BV, Zhao Z, Jung JU. Zeng J, et al. Among authors: gradinaru v. Cell Rep. 2019 Apr 9;27(2):549-560.e6. doi: 10.1016/j.celrep.2018.12.055. Cell Rep. 2019. PMID: 30970257 Free PMC article.

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