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Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern.
Skelly DT, Harding AC, Gilbert-Jaramillo J, Knight ML, Longet S, Brown A, Adele S, Adland E, Brown H; Medawar Laboratory Team; Tipton T, Stafford L, Mentzer AJ, Johnson SA, Amini A; OPTIC (Oxford Protective T cell Immunology for COVID-19) Clinical Group; Tan TK, Schimanski L, Huang KA, Rijal P; PITCH (Protective Immunity T cells in Health Care Worker) Study Group; C-MORE/PHOSP-C Group; Frater J, Goulder P, Conlon CP, Jeffery K, Dold C, Pollard AJ, Sigal A, de Oliveira T, Townsend AR, Klenerman P, Dunachie SJ, Barnes E, Carroll MW, James WS. Skelly DT, et al. Among authors: brown h, brown a. Nat Commun. 2021 Aug 17;12(1):5061. doi: 10.1038/s41467-021-25167-5. Nat Commun. 2021. PMID: 34404775 Free PMC article.
Unique acquisition of cytotoxic T-lymphocyte escape mutants in infant human immunodeficiency virus type 1 infection.
Pillay T, Zhang HT, Drijfhout JW, Robinson N, Brown H, Khan M, Moodley J, Adhikari M, Pfafferott K, Feeney ME, St John A, Holmes EC, Coovadia HM, Klenerman P, Goulder PJ, Phillips RE. Pillay T, et al. Among authors: brown h. J Virol. 2005 Sep;79(18):12100-5. doi: 10.1128/JVI.79.18.12100-12105.2005. J Virol. 2005. PMID: 16140787 Free PMC article.
Failure to detect xenotropic murine leukemia virus-related virus in blood of individuals at high risk of blood-borne viral infections.
Barnes E, Flanagan P, Brown A, Robinson N, Brown H, McClure M, Oxenius A, Collier J, Weber J, Günthard HF, Hirschel B, Fidler S, Phillips R, Frater J. Barnes E, et al. Among authors: brown h, brown a. J Infect Dis. 2010 Nov 15;202(10):1482-5. doi: 10.1086/657167. Epub 2010 Oct 11. J Infect Dis. 2010. PMID: 20936982 Free article.
Immunological biomarkers predict HIV-1 viral rebound after treatment interruption.
Hurst J, Hoffmann M, Pace M, Williams JP, Thornhill J, Hamlyn E, Meyerowitz J, Willberg C, Koelsch KK, Robinson N, Brown H, Fisher M, Kinloch S, Cooper DA, Schechter M, Tambussi G, Fidler S, Babiker A, Weber J, Kelleher AD, Phillips RE, Frater J. Hurst J, et al. Among authors: brown h. Nat Commun. 2015 Oct 9;6:8495. doi: 10.1038/ncomms9495. Nat Commun. 2015. PMID: 26449164 Free PMC article. Clinical Trial.
CD32-Expressing CD4 T Cells Are Phenotypically Diverse and Can Contain Proviral HIV DNA.
Martin GE, Pace M, Thornhill JP, Phetsouphanh C, Meyerowitz J, Gossez M, Brown H, Olejniczak N, Lwanga J, Ramjee G, Kaleebu P, Porter K, Willberg CB, Klenerman P, Nwokolo N, Fox J, Fidler S, Frater J. Martin GE, et al. Among authors: brown h. Front Immunol. 2018 May 4;9:928. doi: 10.3389/fimmu.2018.00928. eCollection 2018. Front Immunol. 2018. PMID: 29780387 Free PMC article.
CD32 expressing doublets in HIV-infected gut-associated lymphoid tissue are associated with a T follicular helper cell phenotype.
Thornhill JP, Pace M, Martin GE, Hoare J, Peake S, Herrera C, Phetsouphanh C, Meyerowitz J, Hopkins E, Brown H, Dunn P, Olejniczak N, Willberg C, Klenerman P, Goldin R, Fox J, Fidler S, Frater J; CHERUB investigators. Thornhill JP, et al. Among authors: brown h. Mucosal Immunol. 2019 Sep;12(5):1212-1219. doi: 10.1038/s41385-019-0180-2. Epub 2019 Jun 25. Mucosal Immunol. 2019. PMID: 31239514 Free article.
Levels of Human Immunodeficiency Virus DNA Are Determined Before ART Initiation and Linked to CD8 T-Cell Activation and Memory Expansion.
Martin GE, Pace M, Shearer FM, Zilber E, Hurst J, Meyerowitz J, Thornhill JP, Lwanga J, Brown H, Robinson N, Hopkins E, Olejniczak N, Nwokolo N, Fox J, Fidler S, Willberg CB, Frater J. Martin GE, et al. Among authors: brown h. J Infect Dis. 2020 Mar 16;221(7):1135-1145. doi: 10.1093/infdis/jiz563. J Infect Dis. 2020. PMID: 31776569 Free PMC article.
T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiviral responses.
Ogbe A, Kronsteiner B, Skelly DT, Pace M, Brown A, Adland E, Adair K, Akhter HD, Ali M, Ali SE, Angyal A, Ansari MA, Arancibia-Cárcamo CV, Brown H, Chinnakannan S, Conlon C, de Lara C, de Silva T, Dold C, Dong T, Donnison T, Eyre D, Flaxman A, Fletcher H, Gardner J, Grist JT, Hackstein CP, Jaruthamsophon K, Jeffery K, Lambe T, Lee L, Li W, Lim N, Matthews PC, Mentzer AJ, Moore SC, Naisbitt DJ, Ogese M, Ogg G, Openshaw P, Pirmohamed M, Pollard AJ, Ramamurthy N, Rongkard P, Rowland-Jones S, Sampson O, Screaton G, Sette A, Stafford L, Thompson C, Thomson PJ, Thwaites R, Vieira V, Weiskopf D, Zacharopoulou P; Oxford Immunology Network Covid-19 Response T Cell Consortium; Oxford Protective T Cell Immunology for COVID-19 (OPTIC) Clinical Team; Turtle L, Klenerman P, Goulder P, Frater J, Barnes E, Dunachie S. Ogbe A, et al. Among authors: brown h, brown a. Nat Commun. 2021 Apr 6;12(1):2055. doi: 10.1038/s41467-021-21856-3. Nat Commun. 2021. PMID: 33824342 Free PMC article.
Epigenetic Features of HIV-Induced T-Cell Exhaustion Persist Despite Early Antiretroviral Therapy.
Martin GE, Sen DR, Pace M, Robinson N, Meyerowitz J, Adland E, Thornhill JP, Jones M, Ogbe A, Parolini L, Olejniczak N, Zacharopoulou P, Brown H, Willberg CB, Nwokolo N, Fox J, Fidler S, Haining WN, Frater J. Martin GE, et al. Among authors: brown h. Front Immunol. 2021 Jun 4;12:647688. doi: 10.3389/fimmu.2021.647688. eCollection 2021. Front Immunol. 2021. PMID: 34149690 Free PMC article. Clinical Trial.
3,832 results