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Autophagy-mitophagy induction attenuates cardiovascular inflammation in a murine model of Kawasaki disease vasculitis.
Marek-Iannucci S, Ozdemir AB, Moreira D, Gomez AC, Lane M, Porritt RA, Lee Y, Shimada K, Abe M, Stotland A, Zemmour D, Parker S, Sanchez-Lopez E, Van Eyk J, Gottlieb RA, Fishbein MC, Karin M, Crother TR, Rivas MN, Arditi M. Marek-Iannucci S, et al. Among authors: karin m. JCI Insight. 2021 Sep 22;6(18):e151981. doi: 10.1172/jci.insight.151981. JCI Insight. 2021. PMID: 34403365 Free PMC article.
Choline kinase inhibition in rheumatoid arthritis.
Guma M, Sanchez-Lopez E, Lodi A, Garcia-Carbonell R, Tiziani S, Karin M, Lacal JC, Firestein GS. Guma M, et al. Among authors: karin m. Ann Rheum Dis. 2015 Jul;74(7):1399-407. doi: 10.1136/annrheumdis-2014-205696. Epub 2014 Oct 1. Ann Rheum Dis. 2015. PMID: 25274633 Free PMC article.
NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria.
Zhong Z, Umemura A, Sanchez-Lopez E, Liang S, Shalapour S, Wong J, He F, Boassa D, Perkins G, Ali SR, McGeough MD, Ellisman MH, Seki E, Gustafsson AB, Hoffman HM, Diaz-Meco MT, Moscat J, Karin M. Zhong Z, et al. Among authors: karin m. Cell. 2016 Feb 25;164(5):896-910. doi: 10.1016/j.cell.2015.12.057. Cell. 2016. PMID: 26919428 Free PMC article.
New mitochondrial DNA synthesis enables NLRP3 inflammasome activation.
Zhong Z, Liang S, Sanchez-Lopez E, He F, Shalapour S, Lin XJ, Wong J, Ding S, Seki E, Schnabl B, Hevener AL, Greenberg HB, Kisseleva T, Karin M. Zhong Z, et al. Among authors: karin m. Nature. 2018 Aug;560(7717):198-203. doi: 10.1038/s41586-018-0372-z. Epub 2018 Jul 25. Nature. 2018. PMID: 30046112 Free PMC article.
Choline Uptake and Metabolism Modulate Macrophage IL-1β and IL-18 Production.
Sanchez-Lopez E, Zhong Z, Stubelius A, Sweeney SR, Booshehri LM, Antonucci L, Liu-Bryan R, Lodi A, Terkeltaub R, Lacal JC, Murphy AN, Hoffman HM, Tiziani S, Guma M, Karin M. Sanchez-Lopez E, et al. Among authors: karin m. Cell Metab. 2019 Jun 4;29(6):1350-1362.e7. doi: 10.1016/j.cmet.2019.03.011. Epub 2019 Apr 11. Cell Metab. 2019. PMID: 30982734 Free PMC article.
720 results