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Loss of Sirt3 accelerates arterial thrombosis by increasing formation of neutrophil extracellular traps and plasma tissue factor activity.
Gaul DS, Weber J, van Tits LJ, Sluka S, Pasterk L, Reiner MF, Calatayud N, Lohmann C, Klingenberg R, Pahla J, Vdovenko D, Tanner FC, Camici GG, Eriksson U, Auwerx J, Mach F, Windecker S, Rodondi N, Lüscher TF, Winnik S, Matter CM. Gaul DS, et al. Among authors: pasterk l. Cardiovasc Res. 2018 Jul 1;114(8):1178-1188. doi: 10.1093/cvr/cvy036. Cardiovasc Res. 2018. PMID: 29444200 Free PMC article.
Gut microbiota-dependent trimethylamine-N-oxide (TMAO) shows a U-shaped association with mortality but not with recurrent venous thromboembolism.
Reiner MF, Müller D, Gobbato S, Stalder O, Limacher A, Bonetti NR, Pasterk L, Méan M, Rodondi N, Aujesky D, Angelillo-Scherrer A, Matter CM, Lüscher TF, Camici GG, von Eckardstein A, Beer JH. Reiner MF, et al. Among authors: pasterk l. Thromb Res. 2019 Feb;174:40-47. doi: 10.1016/j.thromres.2018.12.011. Epub 2018 Dec 6. Thromb Res. 2019. PMID: 30553164
Reduced adrenal stress response in patients on PCSK9 inhibitor therapy.
Meier S, Frick M, Liu M, Saeedi Saravi SS, Montrasio G, Preiss H, Pasterk L, Bonetti N, Egloff M, Schmid HR, Sudano I, Camici GG, Mach F, Luescher TF, Ehret G, Beer JH. Meier S, et al. Among authors: pasterk l. Atherosclerosis. 2021 May;325:63-68. doi: 10.1016/j.atherosclerosis.2021.03.028. Epub 2021 Mar 31. Atherosclerosis. 2021. PMID: 33892329
Long-term dietary supplementation with plant-derived omega-3 fatty acid improves outcome in experimental ischemic stroke.
Bonetti NR, Liberale L, Akhmedov A, Pasterk L, Gobbato S, Puspitasari YM, Vukolic A, Saeedi Saravi SS, Coester B, Horvath C, Osto E, Montecucco F, Lüscher TF, Beer JH, Camici GG. Bonetti NR, et al. Among authors: pasterk l. Atherosclerosis. 2021 May;325:89-98. doi: 10.1016/j.atherosclerosis.2021.04.005. Epub 2021 Apr 20. Atherosclerosis. 2021. PMID: 33915355 Free article.
Endothelial SIRT6 deficiency promotes arterial thrombosis in mice.
Gaul DS, Calatayud N, Pahla J, Bonetti NR, Wang YJ, Weber J, Ambrosini S, Liberale L, Costantino S, Mohammed SA, Kraler S, Van Tits LJ, Pasterk L, Vdovenko D, Akhmedov A, Ruschitzka F, Paneni F, Lüscher TF, Camici GG, Matter CM. Gaul DS, et al. Among authors: pasterk l. J Mol Cell Cardiol. 2023 Jan;174:56-62. doi: 10.1016/j.yjmcc.2022.11.005. Epub 2022 Nov 19. J Mol Cell Cardiol. 2023. PMID: 36414111 Free article.
Intravenously administered APAC, a dual AntiPlatelet AntiCoagulant, targets arterial injury site to inhibit platelet thrombus formation and tissue factor activity in mice.
Bonetti NR, Jouppila AS, Saeedi Saravi SS, Cooley BC, Pasterk L, Liberale LL, Gobbato S, Lüscher TF, Camici GG, Lassila RP, Beer JH. Bonetti NR, et al. Among authors: pasterk l. Thromb Res. 2023 Aug;228:163-171. doi: 10.1016/j.thromres.2023.04.010. Epub 2023 Apr 25. Thromb Res. 2023. PMID: 37331119 Free article.
Mild endothelial dysfunction in Sirt3 knockout mice fed a high-cholesterol diet: protective role of a novel C/EBP-β-dependent feedback regulation of SOD2.
Winnik S, Gaul DS, Siciliani G, Lohmann C, Pasterk L, Calatayud N, Weber J, Eriksson U, Auwerx J, van Tits LJ, Lüscher TF, Matter CM. Winnik S, et al. Among authors: pasterk l. Basic Res Cardiol. 2016 May;111(3):33. doi: 10.1007/s00395-016-0552-7. Epub 2016 Apr 12. Basic Res Cardiol. 2016. PMID: 27071400 Free PMC article.
17 results