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The pathogenesis of mesothelioma is driven by a dysregulated translatome.
Grosso S, Marini A, Gyuraszova K, Voorde JV, Sfakianos A, Garland GD, Tenor AR, Mordue R, Chernova T, Morone N, Sereno M, Smith CP, Officer L, Farahmand P, Rooney C, Sumpton D, Das M, Teodósio A, Ficken C, Martin MG, Spriggs RV, Sun XM, Bushell M, Sansom OJ, Murphy D, MacFarlane M, Le Quesne JPC, Willis AE. Grosso S, et al. Among authors: spriggs rv. Nat Commun. 2021 Aug 13;12(1):4920. doi: 10.1038/s41467-021-25173-7. Nat Commun. 2021. PMID: 34389715 Free PMC article.
In situ growth in early lung adenocarcinoma may represent precursor growth or invasive clone outgrowth-a clinically relevant distinction.
Moore DA, Sereno M, Das M, Baena Acevedo JD, Sinnadurai S, Smith C, McSweeney A, Su X, Officer L, Jones C, Dudek K, Guttery D, Taniere P, Spriggs RV, Le Quesne J. Moore DA, et al. Among authors: spriggs rv. Mod Pathol. 2019 Jul;32(8):1095-1105. doi: 10.1038/s41379-019-0257-1. Epub 2019 Apr 1. Mod Pathol. 2019. PMID: 30932019 Free article.
RTN3 Is a Novel Cold-Induced Protein and Mediates Neuroprotective Effects of RBM3.
Bastide A, Peretti D, Knight JR, Grosso S, Spriggs RV, Pichon X, Sbarrato T, Roobol A, Roobol J, Vito D, Bushell M, von der Haar T, Smales CM, Mallucci GR, Willis AE. Bastide A, et al. Among authors: spriggs rv. Curr Biol. 2017 Mar 6;27(5):638-650. doi: 10.1016/j.cub.2017.01.047. Epub 2017 Feb 23. Curr Biol. 2017. PMID: 28238655 Free PMC article.
A ribosome-related signature in peripheral blood CLL B cells is linked to reduced survival following treatment.
Sbarrato T, Horvilleur E, Pöyry T, Hill K, Chaplin LC, Spriggs RV, Stoneley M, Wilson L, Jayne S, Vulliamy T, Beck D, Dokal I, Dyer MJ, Yeomans AM, Packham G, Bushell M, Wagner SD, Willis AE. Sbarrato T, et al. Among authors: spriggs rv. Cell Death Dis. 2016 Jun 2;7(6):e2249. doi: 10.1038/cddis.2016.148. Cell Death Dis. 2016. PMID: 27253413 Free PMC article.
A role for eukaryotic initiation factor 4B overexpression in the pathogenesis of diffuse large B-cell lymphoma.
Horvilleur E, Sbarrato T, Hill K, Spriggs RV, Screen M, Goodrem PJ, Sawicka K, Chaplin LC, Touriol C, Packham G, Potter KN, Dirnhofer S, Tzankov A, Dyer MJ, Bushell M, MacFarlane M, Willis AE. Horvilleur E, et al. Among authors: spriggs rv. Leukemia. 2014 May;28(5):1092-102. doi: 10.1038/leu.2013.295. Epub 2013 Oct 18. Leukemia. 2014. PMID: 24135829 Free PMC article.
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