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Novel hydroxybenzylamine-deoxyvasicinone hybrids as anticholinesterase therapeutics for Alzheimer's disease.
Bioorg Med Chem. 2021 Sep 1;45:116311. doi: 10.1016/j.bmc.2021.116311. Epub 2021 Jul 14.
Bioorg Med Chem. 2021.
PMID: 34304133
Free PMC article.
Design and Synthesis of Novel Hybrid 8-Hydroxy Quinoline-Indole Derivatives as Inhibitors of Aβ Self-Aggregation and Metal Chelation-Induced Aβ Aggregation.
Bowroju SK, Mainali N, Ayyadevara S, Penthala NR, Krishnamachari S, Kakraba S, Reis RJS, Crooks PA.
Bowroju SK, et al.
Molecules. 2020 Aug 8;25(16):3610. doi: 10.3390/molecules25163610.
Molecules. 2020.
PMID: 32784464
Free PMC article.
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Structural modeling of GSK3β implicates the inactive (DFG-out) conformation as the target bound by TDZD analogs.
Balasubramaniam M, Mainali N, Bowroju SK, Atluri P, Penthala NR, Ayyadevera S, Crooks PA, Shmookler Reis RJ.
Balasubramaniam M, et al. Among authors: bowroju sk.
Sci Rep. 2020 Oct 27;10(1):18326. doi: 10.1038/s41598-020-75020-w.
Sci Rep. 2020.
PMID: 33110096
Free PMC article.
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Thiadiazolidinone (TDZD) Analogs Inhibit Aggregation-Mediated Pathology in Diverse Neurodegeneration Models, and Extend C. elegans Life- and Healthspan.
Kakraba S, Ayyadevara S, Mainali N, Balasubramaniam M, Bowroju S, Penthala NR, Atluri R, Barger SW, Griffin ST, Crooks PA, Shmookler Reis RJ.
Kakraba S, et al.
Pharmaceuticals (Basel). 2023 Oct 20;16(10):1498. doi: 10.3390/ph16101498.
Pharmaceuticals (Basel). 2023.
PMID: 37895969
Free PMC article.
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I2/DMSO-catalyzed one-pot approach for the synthesis of 1,3,4-selenadiazoles.
Bowroju SK, Bavanthula R.
Bowroju SK, et al.
RSC Adv. 2021 Feb 2;11(10):5724-5728. doi: 10.1039/d0ra10576g. eCollection 2021 Jan 28.
RSC Adv. 2021.
PMID: 35423114
Free PMC article.
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