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Actinomycin D Targets NPM1c-Primed Mitochondria to Restore PML-Driven Senescence in AML Therapy.
Wu HC, Rérolle D, Berthier C, Hleihel R, Sakamoto T, Quentin S, Benhenda S, Morganti C, Wu C, Conte L, Rimsky S, Sebert M, Clappier E, Souquere S, Gachet S, Soulier J, Durand S, Trowbridge JJ, Bénit P, Rustin P, El Hajj H, Raffoux E, Ades L, Itzykson R, Dombret H, Fenaux P, Espeli O, Kroemer G, Brunetti L, Mak TW, Lallemand-Breitenbach V, Bazarbachi A, Falini B, Ito K, Martelli MP, de Thé H. Wu HC, et al. Among authors: sakamoto t. Cancer Discov. 2021 Dec 1;11(12):3198-3213. doi: 10.1158/2159-8290.CD-21-0177. Cancer Discov. 2021. PMID: 34301789 Free PMC article.
Opposing effects of NPM1wt and NPM1c mutants on AKT signaling in AML.
Ren Z, Shrestha M, Sakamoto T, Melkman T, Meng L, Cairns RA, Zacksenhaus E, Mak TW, Stambolic V, Minden MD, Wang JA. Ren Z, et al. Among authors: sakamoto t. Leukemia. 2020 Apr;34(4):1172-1176. doi: 10.1038/s41375-019-0621-7. Epub 2019 Nov 14. Leukemia. 2020. PMID: 31728055 No abstract available.
IDH2 and TET2 mutations synergize to modulate T Follicular Helper cell functional interaction with the AITL microenvironment.
Leca J, Lemonnier F, Meydan C, Foox J, El Ghamrasni S, Mboumba DL, Duncan GS, Fortin J, Sakamoto T, Tobin C, Hodgson K, Haight J, Smith LK, Elia AJ, Butler D, Berger T, de Leval L, Mason CE, Melnick A, Gaulard P, Mak TW. Leca J, et al. Among authors: sakamoto t. Cancer Cell. 2023 Feb 13;41(2):323-339.e10. doi: 10.1016/j.ccell.2023.01.003. Epub 2023 Feb 2. Cancer Cell. 2023. PMID: 36736318 Free article.
Distinct and opposite effects of leukemogenic Idh and Tet2 mutations in hematopoietic stem and progenitor cells.
Fortin J, Chiang MF, Meydan C, Foox J, Ramachandran P, Leca J, Lemonnier F, Li WY, Gams MS, Sakamoto T, Chu M, Tobin C, Laugesen E, Robinson TM, You-Ten A, Butler DJ, Berger T, Minden MD, Levine RL, Guidos CJ, Melnick AM, Mason CE, Mak TW. Fortin J, et al. Among authors: sakamoto t. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2208176120. doi: 10.1073/pnas.2208176120. Epub 2023 Jan 18. Proc Natl Acad Sci U S A. 2023. PMID: 36652477 Free PMC article.
Proteomic analysis of serum extracellular vesicles reveals Fibulin-3 as a new marker predicting liver-related events in MASLD.
Sakane S, Hikita H, Shirai K, Sakamoto T, Narumi R, Adachi J, Kakita N, Yamada Y, Toyoda H, Takahashi H, Suda G, Kai M, Tahata Y, Sakamori R, Kumazaki S, Fukumoto K, Myojin Y, Murai K, Kodama T, Tatsumi T, Tomonaga T, Sakamoto N, Morii E, Takehara T. Sakane S, et al. Among authors: sakamoto t. Hepatol Commun. 2024 Jun 3;8(6):e0448. doi: 10.1097/HC9.0000000000000448. eCollection 2024 Jun 1. Hepatol Commun. 2024. PMID: 38829196
Clinical Characteristics and Progression of Pachychoroid and Conventional Geographic Atrophy.
Sato Y, Ueda-Arakawa N, Takahashi A, Miyake M, Mori Y, Miyara Y, Hara C, Kitajima Y, Maruko R, Kawai M, Takahashi H, Koizumi H, Maruyama-Inoue M, Yanagi Y, Iida T, Takahashi K, Sakamoto T, Tsujikawa A. Sato Y, et al. Among authors: sakamoto t. Ophthalmol Sci. 2024 Apr 10;4(5):100528. doi: 10.1016/j.xops.2024.100528. eCollection 2024 Sep-Oct. Ophthalmol Sci. 2024. PMID: 38827489 Free PMC article.
5,278 results