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No evidence for differential gene expression in major depressive disorder PBMCs, but robust evidence of elevated biological ageing.
Cole JJ, McColl A, Shaw R, Lynall ME, Cowen PJ, de Boer P, Drevets WC, Harrison N, Pariante C, Pointon L; NIMA consortium; Goodyear C, Bullmore E, Cavanagh J. Cole JJ, et al. Among authors: drevets wc. Transl Psychiatry. 2021 Jul 22;11(1):404. doi: 10.1038/s41398-021-01506-4. Transl Psychiatry. 2021. PMID: 34294682 Free PMC article.
Replicable and Coupled Changes in Innate and Adaptive Immune Gene Expression in Two Case-Control Studies of Blood Microarrays in Major Depressive Disorder.
Leday GGR, Vértes PE, Richardson S, Greene JR, Regan T, Khan S, Henderson R, Freeman TC, Pariante CM, Harrison NA; MRC Immunopsychiatry Consortium; Perry VH, Drevets WC, Wittenberg GM, Bullmore ET. Leday GGR, et al. Among authors: drevets wc. Biol Psychiatry. 2018 Jan 1;83(1):70-80. doi: 10.1016/j.biopsych.2017.01.021. Epub 2017 Jul 6. Biol Psychiatry. 2018. PMID: 28688579 Free PMC article.
Treatment-resistant depression and peripheral C-reactive protein.
Chamberlain SR, Cavanagh J, de Boer P, Mondelli V, Jones DNC, Drevets WC, Cowen PJ, Harrison NA, Pointon L, Pariante CM, Bullmore ET. Chamberlain SR, et al. Among authors: drevets wc. Br J Psychiatry. 2019 Jan;214(1):11-19. doi: 10.1192/bjp.2018.66. Epub 2018 May 16. Br J Psychiatry. 2019. PMID: 29764522 Free PMC article.
Major Depressive Disorder Is Associated With Differential Expression of Innate Immune and Neutrophil-Related Gene Networks in Peripheral Blood: A Quantitative Review of Whole-Genome Transcriptional Data From Case-Control Studies.
Wittenberg GM, Greene J, Vértes PE, Drevets WC, Bullmore ET. Wittenberg GM, et al. Among authors: drevets wc. Biol Psychiatry. 2020 Oct 15;88(8):625-637. doi: 10.1016/j.biopsych.2020.05.006. Epub 2020 May 13. Biol Psychiatry. 2020. PMID: 32653108 Free article.
Whole-blood expression of inflammasome- and glucocorticoid-related mRNAs correctly separates treatment-resistant depressed patients from drug-free and responsive patients in the BIODEP study.
Cattaneo A, Ferrari C, Turner L, Mariani N, Enache D, Hastings C, Kose M, Lombardo G, McLaughlin AP, Nettis MA, Nikkheslat N, Sforzini L, Worrell C, Zajkowska Z, Cattane N, Lopizzo N, Mazzelli M, Pointon L, Cowen PJ, Cavanagh J, Harrison NA, de Boer P, Jones D, Drevets WC, Mondelli V, Bullmore ET; Neuroimmunology of Mood Disorders and Alzheimer’s Disease (NIMA) Consortium; Pariante CM. Cattaneo A, et al. Among authors: drevets wc. Transl Psychiatry. 2020 Jul 23;10(1):232. doi: 10.1038/s41398-020-00874-7. Transl Psychiatry. 2020. PMID: 32699209 Free PMC article.
A Modest Increase in 11C-PK11195-Positron Emission Tomography TSPO Binding in Depression Is Not Associated With Serum C-Reactive Protein or Body Mass Index.
Schubert JJ, Veronese M, Fryer TD, Manavaki R, Kitzbichler MG, Nettis MA, Mondelli V, Pariante CM, Bullmore ET; NIMA Consortium; Turkheimer FE. Schubert JJ, et al. Biol Psychiatry Cogn Neurosci Neuroimaging. 2021 Jul;6(7):716-724. doi: 10.1016/j.bpsc.2020.12.017. Epub 2021 Jan 28. Biol Psychiatry Cogn Neurosci Neuroimaging. 2021. PMID: 33515765 Free PMC article.
Peripheral Blood Cell-Stratified Subgroups of Inflamed Depression.
Lynall ME, Turner L, Bhatti J, Cavanagh J, de Boer P, Mondelli V, Jones D, Drevets WC, Cowen P, Harrison NA, Pariante CM, Pointon L, Clatworthy MR, Bullmore E; Neuroimmunology of Mood Disorders and Alzheimer’s Disease (NIMA) Consortium. Lynall ME, et al. Among authors: drevets wc. Biol Psychiatry. 2020 Jul 15;88(2):185-196. doi: 10.1016/j.biopsych.2019.11.017. Epub 2019 Dec 2. Biol Psychiatry. 2020. PMID: 32000983 Free article.
Correction: Whole-blood expression of inflammasome- and glucocorticoid-related mRNAs correctly separates treatment-resistant depressed patients from drug-free and responsive patients in the BIODEP study.
Cattaneo A, Ferrari C, Turner L, Mariani N, Enache D, Hastings C, Kose M, Lombardo G, McLaughlin AP, Nettis MA, Nikkheslat N, Sforzini L, Worrell C, Zajkowska Z, Cattane N, Lopizzo N, Mazzelli M, Pointon L, Cowen PJ, Cavanagh J, Harrison NA, de Boer P, Jones D, Drevets WC, Mondelli V, Bullmore ET; Neuroimmunology of Mood Disorders and Alzheimer’s Disease (NIMA) Consortium; Pariante CM. Cattaneo A, et al. Among authors: drevets wc. Transl Psychiatry. 2020 Oct 19;10(1):352. doi: 10.1038/s41398-020-01044-5. Transl Psychiatry. 2020. PMID: 33077715 Free PMC article.
344 results