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A novel RyR1-selective inhibitor prevents and rescues sudden death in mouse models of malignant hyperthermia and heat stroke.
Yamazawa T, Kobayashi T, Kurebayashi N, Konishi M, Noguchi S, Inoue T, Inoue YU, Nishino I, Mori S, Iinuma H, Manaka N, Kagechika H, Uryash A, Adams J, Lopez JR, Liu X, Diggle C, Allen PD, Kakizawa S, Ikeda K, Lin B, Ikemi Y, Nunomura K, Nakagawa S, Sakurai T, Murayama T. Yamazawa T, et al. Among authors: murayama t. Nat Commun. 2021 Jul 13;12(1):4293. doi: 10.1038/s41467-021-24644-1. Nat Commun. 2021. PMID: 34257294 Free PMC article.
Putative roles of type 3 ryanodine receptor isoforms (RyR3).
Ogawa Y, Kurebayashi N, Murayama T. Ogawa Y, et al. Among authors: murayama t. Trends Cardiovasc Med. 2000 Feb;10(2):65-70. doi: 10.1016/s1050-1738(00)00050-5. Trends Cardiovasc Med. 2000. PMID: 11150732 Review.
Changes in Ca2+ handling in adult MG29-deficient skeletal muscle.
Kurebayashi N, Takeshima H, Nishi M, Murayama T, Suzuki E, Ogawa Y. Kurebayashi N, et al. Among authors: murayama t. Biochem Biophys Res Commun. 2003 Oct 31;310(4):1266-72. doi: 10.1016/j.bbrc.2003.09.146. Biochem Biophys Res Commun. 2003. PMID: 14559251
RyR1 exhibits lower gain of CICR activity than RyR3 in the SR: evidence for selective stabilization of RyR1 channel.
Murayama T, Ogawa Y. Murayama T, et al. Am J Physiol Cell Physiol. 2004 Jul;287(1):C36-45. doi: 10.1152/ajpcell.00395.2003. Epub 2004 Feb 25. Am J Physiol Cell Physiol. 2004. PMID: 14985235 Free article.
We showed that frog alpha-ryanodine receptor (alpha-RyR) had a lower gain of Ca(2+)-induced Ca(2+) release (CICR) activity than beta-RyR in sarcoplasmic reticulum (SR) vesicles, indicating selective "stabilization" of the former isoform (Murayama T and Ogawa Y. J Bi …
We showed that frog alpha-ryanodine receptor (alpha-RyR) had a lower gain of Ca(2+)-induced Ca(2+) release (CICR) activity than beta-RyR in …
1,147 results