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Gene therapy for aromatic L-amino acid decarboxylase deficiency by MR-guided direct delivery of AAV2-AADC to midbrain dopaminergic neurons.
Pearson TS, Gupta N, San Sebastian W, Imamura-Ching J, Viehoever A, Grijalvo-Perez A, Fay AJ, Seth N, Lundy SM, Seo Y, Pampaloni M, Hyland K, Smith E, de Oliveira Barbosa G, Heathcock JC, Minnema A, Lonser R, Elder JB, Leonard J, Larson P, Bankiewicz KS. Pearson TS, et al. Among authors: larson p. Nat Commun. 2021 Jul 12;12(1):4251. doi: 10.1038/s41467-021-24524-8. Nat Commun. 2021. PMID: 34253733 Free PMC article. Clinical Trial.
Striatal volume differences between non-human and human primates.
Yin D, Valles FE, Fiandaca MS, Forsayeth J, Larson P, Starr P, Bankiewicz KS. Yin D, et al. Among authors: larson p. J Neurosci Methods. 2009 Jan 30;176(2):200-5. doi: 10.1016/j.jneumeth.2008.08.027. Epub 2008 Sep 2. J Neurosci Methods. 2009. PMID: 18809434 Free PMC article.
Safety and tolerability of putaminal AADC gene therapy for Parkinson disease.
Christine CW, Starr PA, Larson PS, Eberling JL, Jagust WJ, Hawkins RA, VanBrocklin HF, Wright JF, Bankiewicz KS, Aminoff MJ. Christine CW, et al. Among authors: larson ps. Neurology. 2009 Nov 17;73(20):1662-9. doi: 10.1212/WNL.0b013e3181c29356. Epub 2009 Oct 14. Neurology. 2009. PMID: 19828868 Free PMC article. Clinical Trial.
Novel platform for MRI-guided convection-enhanced delivery of therapeutics: preclinical validation in nonhuman primate brain.
Richardson RM, Kells AP, Martin AJ, Larson PS, Starr PA, Piferi PG, Bates G, Tansey L, Rosenbluth KH, Bringas JR, Berger MS, Bankiewicz KS. Richardson RM, et al. Among authors: larson ps. Stereotact Funct Neurosurg. 2011;89(3):141-51. doi: 10.1159/000323544. Epub 2011 Apr 14. Stereotact Funct Neurosurg. 2011. PMID: 21494065 Free PMC article.
Long-term evaluation of a phase 1 study of AADC gene therapy for Parkinson's disease.
Mittermeyer G, Christine CW, Rosenbluth KH, Baker SL, Starr P, Larson P, Kaplan PL, Forsayeth J, Aminoff MJ, Bankiewicz KS. Mittermeyer G, et al. Among authors: larson p. Hum Gene Ther. 2012 Apr;23(4):377-81. doi: 10.1089/hum.2011.220. Epub 2012 Apr 10. Hum Gene Ther. 2012. PMID: 22424171 Free PMC article. Clinical Trial.
784 results