Borthwick LA - Search Results

1

A Mammalian Target of Rapamycin-Perilipin 3 (mTORC1-Plin3) Pathway is essential to Activate Lipophagy and Protects Against Hepatosteatosis.

Garcia-Macia M, Santos-Ledo A, Leslie J, Paish HL, Collins AL, Scott RS, Watson A, Burgoyne RA, White S, French J, Hammond J, Borthwick LA, Mann J, Bolaños JP, Korolchuk VI, Oakley F, Mann DA. Garcia-Macia M, et al. Among authors: borthwick la. Hepatology. 2021 Dec;74(6):3441-3459. doi: 10.1002/hep.32048. Epub 2021 Sep 21. Hepatology. 2021. PMID: 34233024 Free article.

2

Transforming Growth Factor-β1 (TGF-β1) Driven Epithelial to Mesenchymal Transition (EMT) is Accentuated by Tumour Necrosis Factor α (TNFα) via Crosstalk Between the SMAD and NF-κB Pathways.

Borthwick LA, Gardner A, De Soyza A, Mann DA, Fisher AJ. Borthwick LA, et al. Cancer Microenviron. 2012 Apr;5(1):45-57. doi: 10.1007/s12307-011-0080-9. Epub 2011 Jul 27. Cancer Microenviron. 2012. PMID: 21792635 Free PMC article.

3

The critical role of TAK1 in accentuated epithelial to mesenchymal transition in obliterative bronchiolitis after lung transplantation.

Gardner A, Fisher AJ, Richter C, Johnson GE, Moisey EJ, Brodlie M, Ward C, Krippner-Heidenreich A, Mann DA, Borthwick LA. Gardner A, et al. Among authors: borthwick la. Am J Pathol. 2012 Jun;180(6):2293-308. doi: 10.1016/j.ajpath.2012.02.022. Epub 2012 Apr 21. Am J Pathol. 2012. PMID: 22525462 Free PMC article.

4

Inhibition of RelA-Ser536 phosphorylation by a competing peptide reduces mouse liver fibrosis without blocking the innate immune response.

Moles A, Sanchez AM, Banks PS, Murphy LB, Luli S, Borthwick L, Fisher A, O'Reilly S, van Laar JM, White SA, Perkins ND, Burt AD, Mann DA, Oakley F. Moles A, et al. Hepatology. 2013 Feb;57(2):817-28. doi: 10.1002/hep.26068. Epub 2013 Jan 8. Hepatology. 2013. PMID: 22996371 Free PMC article.

5

IL-1α released from damaged epithelial cells is sufficient and essential to trigger inflammatory responses in human lung fibroblasts.

Suwara MI, Green NJ, Borthwick LA, Mann J, Mayer-Barber KD, Barron L, Corris PA, Farrow SN, Wynn TA, Fisher AJ, Mann DA. Suwara MI, et al. Among authors: borthwick la. Mucosal Immunol. 2014 May;7(3):684-93. doi: 10.1038/mi.2013.87. Epub 2013 Oct 30. Mucosal Immunol. 2014. PMID: 24172847 Free PMC article.

6

How reliable are sino-nasal cell lines for studying the pathophysiology of chronic rhinosinusitis?

Ball SL, Suwara MI, Borthwick LA, Wilson JA, Mann DA, Fisher AJ. Ball SL, et al. Among authors: borthwick la. Ann Otol Rhinol Laryngol. 2015 Jun;124(6):437-42. doi: 10.1177/0003489414565003. Epub 2014 Dec 23. Ann Otol Rhinol Laryngol. 2015. PMID: 25539661 Free PMC article.

7

A potential mode of action for Anakinra in patients with arthrofibrosis following total knee arthroplasty.

Dixon D, Coates J, del Carpio Pons A, Horabin J, Walker A, Abdul N, Kalson NS, Brewster NT, Weir DJ, Deehan DJ, Mann DA, Borthwick LA. Dixon D, et al. Among authors: borthwick la. Sci Rep. 2015 Nov 10;5:16466. doi: 10.1038/srep16466. Sci Rep. 2015. PMID: 26553966 Free PMC article.

8

Fibrosis is a common outcome following total knee arthroplasty.

Abdul N, Dixon D, Walker A, Horabin J, Smith N, Weir DJ, Brewster NT, Deehan DJ, Mann DA, Borthwick LA. Abdul N, et al. Among authors: borthwick la. Sci Rep. 2015 Nov 10;5:16469. doi: 10.1038/srep16469. Sci Rep. 2015. PMID: 26553967 Free PMC article.

9

Pseudomonas aeruginosa Induced Airway Epithelial Injury Drives Fibroblast Activation: A Mechanism in Chronic Lung Allograft Dysfunction.

Borthwick LA, Suwara MI, Carnell SC, Green NJ, Mahida R, Dixon D, Gillespie CS, Cartwright TN, Horabin J, Walker A, Olin E, Rangar M, Gardner A, Mann J, Corris PA, Mann DA, Fisher AJ. Borthwick LA, et al. Am J Transplant. 2016 Jun;16(6):1751-65. doi: 10.1111/ajt.13690. Epub 2016 Feb 26. Am J Transplant. 2016. PMID: 26714197 Free PMC article.

10

Liver: Osteopontin and HMGB1: novel regulators of HSC activation.

Borthwick LA, Mann DA. Borthwick LA, et al. Nat Rev Gastroenterol Hepatol. 2016 Jun;13(6):320-2. doi: 10.1038/nrgastro.2016.58. Epub 2016 Apr 14. Nat Rev Gastroenterol Hepatol. 2016. PMID: 27075262 No abstract available.

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