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Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease.
Chu X, Jaeger M, Beumer J, Bakker OB, Aguirre-Gamboa R, Oosting M, Smeekens SP, Moorlag S, Mourits VP, Koeken VACM, de Bree C, Jansen T, Mathews IT, Dao K, Najhawan M, Watrous JD, Joosten I, Sharma S, Koenen HJPM, Withoff S, Jonkers IH, Netea-Maier RT, Xavier RJ, Franke L, Xu CJ, Joosten LAB, Sanna S, Jain M, Kumar V, Clevers H, Wijmenga C, Netea MG, Li Y. Chu X, et al. Among authors: wijmenga c. Genome Biol. 2021 Jul 6;22(1):198. doi: 10.1186/s13059-021-02413-z. Genome Biol. 2021. PMID: 34229738 Free PMC article.
A strategy to search for common obesity and type 2 diabetes genes.
Elbers CC, Onland-Moret NC, Franke L, Niehoff AG, van der Schouw YT, Wijmenga C. Elbers CC, et al. Among authors: wijmenga c. Trends Endocrinol Metab. 2007 Jan-Feb;18(1):19-26. doi: 10.1016/j.tem.2006.11.003. Epub 2006 Nov 28. Trends Endocrinol Metab. 2007. PMID: 17126559 Review.
Neutrophil recruitment and barrier impairment in celiac disease: a genomic study.
Diosdado B, van Bakel H, Strengman E, Franke L, van Oort E, Mulder CJ, Wijmenga C, Wapenaar MC. Diosdado B, et al. Among authors: wijmenga c. Clin Gastroenterol Hepatol. 2007 May;5(5):574-81. doi: 10.1016/j.cgh.2006.11.014. Epub 2007 Mar 2. Clin Gastroenterol Hepatol. 2007. PMID: 17336591
HHEX gene polymorphisms are associated with type 2 diabetes in the Dutch Breda cohort.
van Vliet-Ostaptchouk JV, Onland-Moret NC, van Haeften TW, Franke L, Elbers CC, Shiri-Sverdlov R, van der Schouw YT, Hofker MH, Wijmenga C. van Vliet-Ostaptchouk JV, et al. Among authors: wijmenga c. Eur J Hum Genet. 2008 May;16(5):652-6. doi: 10.1038/sj.ejhg.5202008. Epub 2008 Jan 30. Eur J Hum Genet. 2008. PMID: 18231124
Genetic analysis of innate immunity in Crohn's disease and ulcerative colitis identifies two susceptibility loci harboring CARD9 and IL18RAP.
Zhernakova A, Festen EM, Franke L, Trynka G, van Diemen CC, Monsuur AJ, Bevova M, Nijmeijer RM, van 't Slot R, Heijmans R, Boezen HM, van Heel DA, van Bodegraven AA, Stokkers PC, Wijmenga C, Crusius JB, Weersma RK. Zhernakova A, et al. Among authors: wijmenga c. Am J Hum Genet. 2008 May;82(5):1202-10. doi: 10.1016/j.ajhg.2008.03.016. Epub 2008 Apr 24. Am J Hum Genet. 2008. PMID: 18439550 Free PMC article.
Genome-wide association study in premature ovarian failure patients suggests ADAMTS19 as a possible candidate gene.
Knauff EA, Franke L, van Es MA, van den Berg LH, van der Schouw YT, Laven JS, Lambalk CB, Hoek A, Goverde AJ, Christin-Maitre S, Hsueh AJ, Wijmenga C, Fauser BC; Dutch POF Consortium. Knauff EA, et al. Among authors: wijmenga c. Hum Reprod. 2009 Sep;24(9):2372-8. doi: 10.1093/humrep/dep197. Epub 2009 Jun 9. Hum Reprod. 2009. PMID: 19508998 Free article.
Human dectin-1 deficiency and mucocutaneous fungal infections.
Ferwerda B, Ferwerda G, Plantinga TS, Willment JA, van Spriel AB, Venselaar H, Elbers CC, Johnson MD, Cambi A, Huysamen C, Jacobs L, Jansen T, Verheijen K, Masthoff L, Morré SA, Vriend G, Williams DL, Perfect JR, Joosten LA, Wijmenga C, van der Meer JW, Adema GJ, Kullberg BJ, Brown GD, Netea MG. Ferwerda B, et al. Among authors: wijmenga c. N Engl J Med. 2009 Oct 29;361(18):1760-7. doi: 10.1056/NEJMoa0901053. N Engl J Med. 2009. PMID: 19864674 Free PMC article.
704 results