Roth A - Search Results

1

CK1δ-Derived Peptides as Novel Tools Inhibiting the Interactions between CK1δ and APP695 to Modulate the Pathogenic Metabolism of APP.

Roth A, Gärtner F, Mayer K, Beyrle J, König I, Knippschild U, Bischof J. Roth A, et al. Int J Mol Sci. 2021 Jun 15;22(12):6423. doi: 10.3390/ijms22126423. Int J Mol Sci. 2021. PMID: 34203978 Free PMC article.

2

Assessing the Inhibitory Potential of Kinase Inhibitors In Vitro: Major Pitfalls and Suggestions for Improving Comparability of Data Using CK1 Inhibitors as an Example.

Roth A, Gihring A, Göser F, Peifer C, Knippschild U, Bischof J. Roth A, et al. Molecules. 2021 Aug 12;26(16):4898. doi: 10.3390/molecules26164898. Molecules. 2021. PMID: 34443486 Free PMC article.

3

Stress-activated kinases as therapeutic targets in pancreatic cancer.

Traub B, Roth A, Kornmann M, Knippschild U, Bischof J. Traub B, et al. Among authors: roth a. World J Gastroenterol. 2021 Aug 14;27(30):4963-4984. doi: 10.3748/wjg.v27.i30.4963. World J Gastroenterol. 2021. PMID: 34497429 Free PMC article. Review.

4

Obesity Prolongs the Inflammatory Response in Mice After Severe Trauma and Attenuates the Splenic Response to the Inflammatory Reflex.

Gärtner F, Gihring A, Roth A, Bischof J, Xu P, Elad L, Wabitsch M, Burster T, Knippschild U. Gärtner F, et al. Among authors: roth a. Front Immunol. 2021 Nov 15;12:745132. doi: 10.3389/fimmu.2021.745132. eCollection 2021. Front Immunol. 2021. PMID: 34867969 Free PMC article.

5

Identification of the Host Substratome of Leishmania-Secreted Casein Kinase 1 Using a SILAC-Based Quantitative Mass Spectrometry Assay.

Smirlis D, Dingli F, Sabatet V, Roth A, Knippschild U, Loew D, Späth GF, Rachidi N. Smirlis D, et al. Among authors: roth a. Front Cell Dev Biol. 2022 Jan 3;9:800098. doi: 10.3389/fcell.2021.800098. eCollection 2021. Front Cell Dev Biol. 2022. PMID: 35047509 Free PMC article.

6

C5-Iminosugar modification of casein kinase 1δ lead 3-(4-fluorophenyl)-5-isopropyl-4-(pyridin-4-yl)isoxazole promotes enhanced inhibitor affinity and selectivity.

von Drathen T, Ure EM, Kirschner S, Roth A, Meier L, Woolhouse AD, Cameron SA, Knippschild U, Peifer C, Luxenburger A. von Drathen T, et al. Among authors: roth a. Arch Pharm (Weinheim). 2022 May;355(5):e2100497. doi: 10.1002/ardp.202100497. Epub 2022 Feb 17. Arch Pharm (Weinheim). 2022. PMID: 35174898

7

CK1 Is a Druggable Regulator of Microtubule Dynamics and Microtubule-Associated Processes.

Roth A, Gihring A, Bischof J, Pan L, Oswald F, Knippschild U. Roth A, et al. Cancers (Basel). 2022 Mar 5;14(5):1345. doi: 10.3390/cancers14051345. Cancers (Basel). 2022. PMID: 35267653 Free PMC article. Review.

8

Comprehensive Characterization of CK1δ-Mediated Tau Phosphorylation in Alzheimer's Disease.

Roth A, Sander A, Oswald MS, Gärtner F, Knippschild U, Bischof J. Roth A, et al. Front Mol Biosci. 2022 Jun 27;9:872171. doi: 10.3389/fmolb.2022.872171. eCollection 2022. Front Mol Biosci. 2022. PMID: 36203870 Free PMC article.

9

Phenotypic Discovery of Triazolo[1,5-c]quinazolines as a First-In-Class Bone Morphogenetic Protein Amplifier Chemotype.

Wesseler F, Lohmann S, Riege D, Halver J, Roth A, Pichlo C, Weber S, Takamiya M, Müller E, Ketzel J, Flegel J, Gihring A, Rastegar S, Bertrand J, Baumann U, Knippschild U, Peifer C, Sievers S, Waldmann H, Schade D. Wesseler F, et al. Among authors: roth a. J Med Chem. 2022 Nov 24;65(22):15263-15281. doi: 10.1021/acs.jmedchem.2c01199. Epub 2022 Nov 8. J Med Chem. 2022. PMID: 36346705

10

Influence of bariatric surgery on the peripheral blood immune system of female patients with morbid obesity revealed by high-dimensional mass cytometry.

Gihring A, Gärtner F, Mayer L, Roth A, Abdelrasoul H, Kornmann M, Elad L, Knippschild U. Gihring A, et al. Among authors: roth a. Front Immunol. 2023 May 11;14:1131893. doi: 10.3389/fimmu.2023.1131893. eCollection 2023. Front Immunol. 2023. PMID: 37266430 Free PMC article.

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