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Paradoxical effect of increased diastolic Ca(2+) release and decreased sinoatrial node activity in a mouse model of catecholaminergic polymorphic ventricular tachycardia.
Neco P, Torrente AG, Mesirca P, Zorio E, Liu N, Priori SG, Napolitano C, Richard S, Benitah JP, Mangoni ME, Gómez AM. Neco P, et al. Among authors: gomez am. Circulation. 2012 Jul 24;126(4):392-401. doi: 10.1161/CIRCULATIONAHA.111.075382. Epub 2012 Jun 18. Circulation. 2012. PMID: 22711277 Free PMC article.
RyR2R420Q catecholaminergic polymorphic ventricular tachycardia mutation induces bradycardia by disturbing the coupled clock pacemaker mechanism.
Wang YY, Mesirca P, Marqués-Sulé E, Zahradnikova A Jr, Villejoubert O, D'Ocon P, Ruiz C, Domingo D, Zorio E, Mangoni ME, Benitah JP, Gómez AM. Wang YY, et al. Among authors: gomez am. JCI Insight. 2017 Apr 20;2(8):e91872. doi: 10.1172/jci.insight.91872. eCollection 2017 Apr 20. JCI Insight. 2017. PMID: 28422759 Free PMC article.
Increased Ca2+ sensitivity of the ryanodine receptor mutant RyR2R4496C underlies catecholaminergic polymorphic ventricular tachycardia.
Fernández-Velasco M, Rueda A, Rizzi N, Benitah JP, Colombi B, Napolitano C, Priori SG, Richard S, Gómez AM. Fernández-Velasco M, et al. Among authors: gomez am. Circ Res. 2009 Jan 30;104(2):201-9, 12p following 209. doi: 10.1161/CIRCRESAHA.108.177493. Epub 2008 Dec 18. Circ Res. 2009. PMID: 19096022 Free PMC article.
Mineralocorticoid modulation of cardiac ryanodine receptor activity is associated with downregulation of FK506-binding proteins.
Gómez AM, Rueda A, Sainte-Marie Y, Pereira L, Zissimopoulos S, Zhu X, Schaub R, Perrier E, Perrier R, Latouche C, Richard S, Picot MC, Jaisser F, Lai FA, Valdivia HH, Benitah JP. Gómez AM, et al. Circulation. 2009 Apr 28;119(16):2179-87. doi: 10.1161/CIRCULATIONAHA.108.805804. Epub 2009 Apr 13. Circulation. 2009. PMID: 19364981 Free article.
Conditional FKBP12.6 overexpression in mouse cardiac myocytes prevents triggered ventricular tachycardia through specific alterations in excitation-contraction coupling.
Gellen B, Fernández-Velasco M, Briec F, Vinet L, LeQuang K, Rouet-Benzineb P, Bénitah JP, Pezet M, Palais G, Pellegrin N, Zhang A, Perrier R, Escoubet B, Marniquet X, Richard S, Jaisser F, Gómez AM, Charpentier F, Mercadier JJ. Gellen B, et al. Among authors: gomez am. Circulation. 2008 Apr 8;117(14):1778-86. doi: 10.1161/CIRCULATIONAHA.107.731893. Epub 2008 Mar 31. Circulation. 2008. PMID: 18378612
462 results