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Tracking HIV-1-Infected Cell Clones Using Integration Site-Specific qPCR.
Viruses. 2021 Jun 25;13(7):1235. doi: 10.3390/v13071235.
Viruses. 2021.
PMID: 34202310
Free PMC article.
Combined HIV-1 sequence and integration site analysis informs viral dynamics and allows reconstruction of replicating viral ancestors.
Patro SC, Brandt LD, Bale MJ, Halvas EK, Joseph KW, Shao W, Wu X, Guo S, Murrell B, Wiegand A, Spindler J, Raley C, Hautman C, Sobolewski M, Fennessey CM, Hu WS, Luke B, Hasson JM, Niyongabo A, Capoferri AA, Keele BF, Milush J, Hoh R, Deeks SG, Maldarelli F, Hughes SH, Coffin JM, Rausch JW, Mellors JW, Kearney MF.
Patro SC, et al. Among authors: joseph kw.
Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25891-25899. doi: 10.1073/pnas.1910334116. Epub 2019 Nov 27.
Proc Natl Acad Sci U S A. 2019.
PMID: 31776247
Free PMC article.
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HIV-1 viremia not suppressible by antiretroviral therapy can originate from large T cell clones producing infectious virus.
Halvas EK, Joseph KW, Brandt LD, Guo S, Sobolewski MD, Jacobs JL, Tumiotto C, Bui JK, Cyktor JC, Keele BF, Morse GD, Bale MJ, Shao W, Kearney MF, Coffin JM, Rausch JW, Wu X, Hughes SH, Mellors JW.
Halvas EK, et al. Among authors: joseph kw.
J Clin Invest. 2020 Nov 2;130(11):5847-5857. doi: 10.1172/JCI138099.
J Clin Invest. 2020.
PMID: 33016926
Free PMC article.
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Deep Sequencing Analysis of Individual HIV-1 Proviruses Reveals Frequent Asymmetric Long Terminal Repeats.
Joseph KW, Halvas EK, Brandt LD, Patro SC, Rausch JW, Chopra A, Mallal S, Kearney MF, Coffin JM, Mellors JW.
Joseph KW, et al.
J Virol. 2022 Jul 13;96(13):e0012222. doi: 10.1128/jvi.00122-22. Epub 2022 Jun 8.
J Virol. 2022.
PMID: 35674431
Free PMC article.
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HIV infected CD4+ T cell clones are more stable than uninfected clones during long-term antiretroviral therapy.
Guo S, Luke BT, Henry AR, Darko S, Brandt LD, Su L, Sun D, Wells D, Joseph KW, Demirov D, Halvas EK, Douek DC, Wu X, Mellors JW, Hughes SH.
Guo S, et al. Among authors: joseph kw.
PLoS Pathog. 2022 Aug 31;18(8):e1010726. doi: 10.1371/journal.ppat.1010726. eCollection 2022 Aug.
PLoS Pathog. 2022.
PMID: 36044447
Free PMC article.
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Intact HIV Proviruses Persist in Children Seven to Nine Years after Initiation of Antiretroviral Therapy in the First Year of Life.
Katusiime MG, Halvas EK, Wright I, Joseph K, Bale MJ, Kirby-McCullough B, Engelbrecht S, Shao W, Hu WS, Cotton MF, Mellors JW, Kearney MF, van Zyl GU.
Katusiime MG, et al.
J Virol. 2020 Jan 31;94(4):e01519-19. doi: 10.1128/JVI.01519-19. Print 2020 Jan 31.
J Virol. 2020.
PMID: 31776265
Free PMC article.
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Insertional activation of STAT3 and LCK by HIV-1 proviruses in T cell lymphomas.
Mellors JW, Guo S, Naqvi A, Brandt LD, Su L, Sun Z, Joseph KW, Demirov D, Halvas EK, Butcher D, Scott B, Hamilton A, Heil M, Karim B, Wu X, Hughes SH.
Mellors JW, et al. Among authors: joseph kw.
Sci Adv. 2021 Oct 15;7(42):eabi8795. doi: 10.1126/sciadv.abi8795. Epub 2021 Oct 13.
Sci Adv. 2021.
PMID: 34644108
Free PMC article.
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