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The lung microenvironment shapes a dysfunctional response of alveolar macrophages in aging.
McQuattie-Pimentel AC, Ren Z, Joshi N, Watanabe S, Stoeger T, Chi M, Lu Z, Sichizya L, Aillon RP, Chen CI, Soberanes S, Chen Z, Reyfman PA, Walter JM, Anekalla KR, Davis JM, Helmin KA, Runyan CE, Abdala-Valencia H, Nam K, Meliton AY, Winter DR, Morimoto RI, Mutlu GM, Bharat A, Perlman H, Gottardi CJ, Ridge KM, Chandel NS, Sznajder JI, Balch WE, Singer BD, Misharin AV, Budinger GRS. McQuattie-Pimentel AC, et al. Among authors: helmin ka. J Clin Invest. 2021 Feb 15;131(4):e140299. doi: 10.1172/JCI140299. J Clin Invest. 2021. PMID: 33586677 Free PMC article.
Mitochondria regulate proliferation in adult cardiac myocytes.
Waypa GB, Smith KA, Mungai PT, Dudley VJ, Helmin KA, Singer BD, Peek CB, Bass J, Beussink-Nelson L, Shah SJ, Ofman G, Wasserstrom JA, Muller WA, Misharin AV, Budinger GRS, Abdala-Valencia H, Chandel NS, Dokic D, Bartom ET, Zhang S, Tatekoshi Y, Mahmoodzadeh A, Ardehali H, Thorp EB, Schumacker PT. Waypa GB, et al. Among authors: helmin ka. J Clin Invest. 2024 May 9:e165482. doi: 10.1172/JCI165482. Online ahead of print. J Clin Invest. 2024. PMID: 38722697 Free article.
A distinctive evolution of alveolar T cell responses is associated with clinical outcomes in unvaccinated patients with SARS-CoV-2 pneumonia.
Markov NS, Ren Z, Senkow KJ, Grant RA, Gao CA, Malsin ES, Sichizya L, Kihshen H, Helmin KA, Jovisic M, Arnold JM, Pérez-Leonor XG, Abdala-Valencia H, Swaminathan S, Nwaezeapu J, Kang M, Rasmussen L, Ozer EA, Lorenzo-Redondo R, Hultquist JF, Simons LM, Rios-Guzman E, Misharin AV, Wunderink RG, Budinger GRS, Singer BD, Morales-Nebreda L; NU SCRIPT Study Investigators. Markov NS, et al. Among authors: helmin ka. bioRxiv [Preprint]. 2023 Dec 14:2023.12.13.571479. doi: 10.1101/2023.12.13.571479. bioRxiv. 2023. PMID: 38168346 Free PMC article. Preprint.
Uncoupling histone H3K4 trimethylation from developmental gene expression via an equilibrium of COMPASS, Polycomb and DNA methylation.
Douillet D, Sze CC, Ryan C, Piunti A, Shah AP, Ugarenko M, Marshall SA, Rendleman EJ, Zha D, Helmin KA, Zhao Z, Cao K, Morgan MA, Singer BD, Bartom ET, Smith ER, Shilatifard A. Douillet D, et al. Among authors: helmin ka. Nat Genet. 2020 Jun;52(6):615-625. doi: 10.1038/s41588-020-0618-1. Epub 2020 May 11. Nat Genet. 2020. PMID: 32393859 Free PMC article.
DNA methylation regulates the neonatal CD4+ T-cell response to pneumonia in mice.
McGrath-Morrow SA, Ndeh R, Helmin KA, Chen SY, Anekalla KR, Abdala-Valencia H, D'Alessio FR, Collaco JM, Singer BD. McGrath-Morrow SA, et al. Among authors: helmin ka. J Biol Chem. 2018 Jul 27;293(30):11772-11783. doi: 10.1074/jbc.RA118.003589. Epub 2018 Jun 4. J Biol Chem. 2018. PMID: 29866884 Free PMC article.
20 results