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A multi-center, single-arm, phase Ib study of pembrolizumab (MK-3475) in combination with chemotherapy for patients with advanced colorectal cancer: HCRN GI14-186.
Herting CJ, Farren MR, Tong Y, Liu Z, O'Neil B, Bekaii-Saab T, Noonan A, McQuinn C, Mace TA, Shaib W, Wu C, El-Rayes BF, Shahda S, Lesinski GB. Herting CJ, et al. Among authors: shahda s. Cancer Immunol Immunother. 2021 Nov;70(11):3337-3348. doi: 10.1007/s00262-021-02986-5. Epub 2021 Jun 23. Cancer Immunol Immunother. 2021. PMID: 34160684 Free PMC article. Clinical Trial.
GI-4000 in KRAS mutant cancers.
Shahda S, O'Neil B. Shahda S, et al. Expert Opin Investig Drugs. 2014 Feb;23(2):273-8. doi: 10.1517/13543784.2014.876408. Epub 2013 Dec 30. Expert Opin Investig Drugs. 2014. PMID: 24372276 Review.
Clinical benefit of a precision medicine based approach for guiding treatment of refractory cancers.
Radovich M, Kiel PJ, Nance SM, Niland EE, Parsley ME, Ferguson ME, Jiang G, Ammakkanavar NR, Einhorn LH, Cheng L, Nassiri M, Davidson DD, Rushing DA, Loehrer PJ, Pili R, Hanna N, Callaghan JT, Skaar TC, Helft PR, Shahda S, O'Neil BH, Schneider BP. Radovich M, et al. Among authors: shahda s. Oncotarget. 2016 Aug 30;7(35):56491-56500. doi: 10.18632/oncotarget.10606. Oncotarget. 2016. PMID: 27447854 Free PMC article.
Phase Ib Study of Wnt Inhibitor Ipafricept with Gemcitabine and nab-paclitaxel in Patients with Previously Untreated Stage IV Pancreatic Cancer.
Dotan E, Cardin DB, Lenz HJ, Messersmith W, O'Neil B, Cohen SJ, Denlinger CS, Shahda S, Astsaturov I, Kapoun AM, Brachmann RK, Uttamsingh S, Stagg RJ, Weekes C. Dotan E, et al. Among authors: shahda s. Clin Cancer Res. 2020 Oct 15;26(20):5348-5357. doi: 10.1158/1078-0432.CCR-20-0489. Epub 2020 Jul 21. Clin Cancer Res. 2020. PMID: 32694153 Free PMC article. Clinical Trial.
A phase 1b dose escalation study of Wnt pathway inhibitor vantictumab in combination with nab-paclitaxel and gemcitabine in patients with previously untreated metastatic pancreatic cancer.
Davis SL, Cardin DB, Shahda S, Lenz HJ, Dotan E, O'Neil BH, Kapoun AM, Stagg RJ, Berlin J, Messersmith WA, Cohen SJ. Davis SL, et al. Among authors: shahda s. Invest New Drugs. 2020 Jun;38(3):821-830. doi: 10.1007/s10637-019-00824-1. Epub 2019 Jul 23. Invest New Drugs. 2020. PMID: 31338636 Free PMC article. Clinical Trial.
44 results