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Notch-IGF1 signaling during liver regeneration drives biliary epithelial cell expansion and inhibits hepatocyte differentiation.
Minnis-Lyons SE, Ferreira-González S, Aleksieva N, Man TY, Gadd VL, Williams MJ, Guest RV, Lu WY, Dwyer BJ, Jamieson T, Nixon C, Van Hul N, Lemaigre FP, McCafferty J, Leclercq IA, Sansom OJ, Boulter L, Forbes SJ. Minnis-Lyons SE, et al. Among authors: mccafferty j. Sci Signal. 2021 Jun 22;14(688):eaay9185. doi: 10.1126/scisignal.aay9185. Sci Signal. 2021. PMID: 34158399
Discovery and optimization of a broadly-neutralizing human monoclonal antibody against long-chain α-neurotoxins from snakes.
Ledsgaard L, Wade J, Jenkins TP, Boddum K, Oganesyan I, Harrison JA, Villar P, Leah RA, Zenobi R, Schoffelen S, Voldborg B, Ljungars A, McCafferty J, Lomonte B, Gutiérrez JM, Laustsen AH, Karatt-Vellatt A. Ledsgaard L, et al. Among authors: mccafferty j. Nat Commun. 2023 Feb 8;14(1):682. doi: 10.1038/s41467-023-36393-4. Nat Commun. 2023. PMID: 36755049 Free PMC article.
Application of phage display to high throughput antibody generation and characterization.
Schofield DJ, Pope AR, Clementel V, Buckell J, Chapple SDj, Clarke KF, Conquer JS, Crofts AM, Crowther SR, Dyson MR, Flack G, Griffin GJ, Hooks Y, Howat WJ, Kolb-Kokocinski A, Kunze S, Martin CD, Maslen GL, Mitchell JN, O'Sullivan M, Perera RL, Roake W, Shadbolt SP, Vincent KJ, Warford A, Wilson WE, Xie J, Young JL, McCafferty J. Schofield DJ, et al. Among authors: mccafferty j. Genome Biol. 2007;8(11):R254. doi: 10.1186/gb-2007-8-11-r254. Genome Biol. 2007. PMID: 18047641 Free PMC article.
Generating a panel of highly specific antibodies to 20 human SH2 domains by phage display.
Pershad K, Pavlovic JD, Gräslund S, Nilsson P, Colwill K, Karatt-Vellatt A, Schofield DJ, Dyson MR, Pawson T, Kay BK, McCafferty J. Pershad K, et al. Among authors: mccafferty j. Protein Eng Des Sel. 2010 Apr;23(4):279-88. doi: 10.1093/protein/gzq003. Epub 2010 Feb 17. Protein Eng Des Sel. 2010. PMID: 20164216 Free PMC article.
132 results