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Allosteric Inhibition of Parkinson's-Linked LRRK2 by Constrained Peptides.
Helton LG, Soliman A, von Zweydorf F, Kentros M, Manschwetus JT, Hall S, Gilsbach B, Ho FY, Athanasopoulos PS, Singh RK, LeClair TJ, Versées W, Raimondi F, Herberg FW, Gloeckner CJ, Rideout H, Kortholt A, Kennedy EJ. Helton LG, et al. Among authors: raimondi f. ACS Chem Biol. 2021 Nov 19;16(11):2326-2338. doi: 10.1021/acschembio.1c00487. Epub 2021 Sep 8. ACS Chem Biol. 2021. PMID: 34496561 Free article.
Cryo-EM structure of the human MT1-Gi signaling complex.
Okamoto HH, Miyauchi H, Inoue A, Raimondi F, Tsujimoto H, Kusakizako T, Shihoya W, Yamashita K, Suno R, Nomura N, Kobayashi T, Iwata S, Nishizawa T, Nureki O. Okamoto HH, et al. Among authors: raimondi f. Nat Struct Mol Biol. 2021 Aug;28(8):694-701. doi: 10.1038/s41594-021-00634-1. Epub 2021 Aug 5. Nat Struct Mol Biol. 2021. PMID: 34354246
PRECOGx: exploring GPCR signaling mechanisms with deep protein representations.
Matic M, Singh G, Carli F, De Oliveira Rosa N, Miglionico P, Magni L, Gutkind JS, Russell RB, Inoue A, Raimondi F. Matic M, et al. Among authors: raimondi f. Nucleic Acids Res. 2022 Jul 5;50(W1):W598-W610. doi: 10.1093/nar/gkac426. Nucleic Acids Res. 2022. PMID: 35639758 Free PMC article.
Structural model of the dimeric Parkinson's protein LRRK2 reveals a compact architecture involving distant interdomain contacts.
Guaitoli G, Raimondi F, Gilsbach BK, Gómez-Llorente Y, Deyaert E, Renzi F, Li X, Schaffner A, Jagtap PK, Boldt K, von Zweydorf F, Gotthardt K, Lorimer DD, Yue Z, Burgin A, Janjic N, Sattler M, Versées W, Ueffing M, Ubarretxena-Belandia I, Kortholt A, Gloeckner CJ. Guaitoli G, et al. Among authors: raimondi f. Proc Natl Acad Sci U S A. 2016 Jul 26;113(30):E4357-66. doi: 10.1073/pnas.1523708113. Epub 2016 Jun 29. Proc Natl Acad Sci U S A. 2016. PMID: 27357661 Free PMC article.
456 results