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Structure of smAKAP and its regulation by PKA-mediated phosphorylation.
Burgers PP, Bruystens J, Burnley RJ, Nikolaev VO, Keshwani M, Wu J, Janssen BJ, Taylor SS, Heck AJ, Scholten A. Burgers PP, et al. Among authors: bruystens j. FEBS J. 2016 Jun;283(11):2132-48. doi: 10.1111/febs.13726. Epub 2016 May 6. FEBS J. 2016. PMID: 27028580 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 35555697
[No title available]
[No authors listed] [No authors listed] PMID: 35555721
A PKA inhibitor motif within SMOOTHENED controls Hedgehog signal transduction.
Happ JT, Arveseth CD, Bruystens J, Bertinetti D, Nelson IB, Olivieri C, Zhang J, Hedeen DS, Zhu JF, Capener JL, Bröckel JW, Vu L, King CC, Ruiz-Perez VL, Ge X, Veglia G, Herberg FW, Taylor SS, Myers BR. Happ JT, et al. Among authors: bruystens j. Nat Struct Mol Biol. 2022 Oct;29(10):990-999. doi: 10.1038/s41594-022-00838-z. Epub 2022 Oct 6. Nat Struct Mol Biol. 2022. PMID: 36202993 Free PMC article.
Targeted Reversible Covalent Modification of a Noncatalytic Lysine of the Krev Interaction Trapped 1 Protein Enables Site-Directed Screening for Protein-Protein Interaction Inhibitors.
Francisco KR, Bruystens J, Varricchio C, McCurdy S, Wu J, Lopez-Ramirez MA, Ginsberg M, Caffrey CR, Brancale A, Gingras AR, Hixon MS, Ballatore C. Francisco KR, et al. Among authors: bruystens j. ACS Pharmacol Transl Sci. 2023 Oct 9;6(11):1651-1658. doi: 10.1021/acsptsci.3c00156. eCollection 2023 Nov 10. ACS Pharmacol Transl Sci. 2023. PMID: 37974623 Free article.
Molecular determinants and signaling effects of PKA RIα phase separation.
Hardy JC, Pool EH, Bruystens JGH, Zhou X, Li Q, Zhou DR, Palay M, Tan G, Chen L, Choi JLC, Lee HN, Strack S, Wang D, Taylor SS, Mehta S, Zhang J. Hardy JC, et al. Among authors: bruystens jgh. Mol Cell. 2024 Apr 18;84(8):1570-1584.e7. doi: 10.1016/j.molcel.2024.03.002. Epub 2024 Mar 26. Mol Cell. 2024. PMID: 38537638
Molecular Determinants and Signaling Effects of PKA RIα Phase Separation.
Hardy JC, Pool EH, Bruystens JGH, Zhou X, Li Q, Zhou DR, Palay M, Tan G, Chen L, Choi JLC, Lee HN, Strack S, Wang D, Taylor SS, Mehta S, Zhang J. Hardy JC, et al. Among authors: bruystens jgh. bioRxiv [Preprint]. 2023 Dec 11:2023.12.10.570836. doi: 10.1101/2023.12.10.570836. bioRxiv. 2023. PMID: 38168176 Free PMC article. Updated. Preprint.
14 results