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Merging C(sp3)-H activation with DNA-encoding.
Fan Z, Zhao S, Liu T, Shen PX, Cui ZN, Zhuang Z, Shao Q, Chen JS, Ratnayake AS, Flanagan ME, Kölmel DK, Piotrowski DW, Richardson P, Yu JQ. Fan Z, et al. Among authors: chen js. Chem Sci. 2020 Sep 7;11(45):12282-12288. doi: 10.1039/d0sc03935g. Chem Sci. 2020. PMID: 34094436 Free PMC article.
Kinetically guided radical-based synthesis of C(sp3)-C(sp3) linkages on DNA.
Wang J, Lundberg H, Asai S, Martín-Acosta P, Chen JS, Brown S, Farrell W, Dushin RG, O'Donnell CJ, Ratnayake AS, Richardson P, Liu Z, Qin T, Blackmond DG, Baran PS. Wang J, et al. Among authors: chen js. Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):E6404-E6410. doi: 10.1073/pnas.1806900115. Epub 2018 Jun 26. Proc Natl Acad Sci U S A. 2018. PMID: 29946037 Free PMC article.
Expanding Reactivity in DNA-Encoded Library Synthesis via Reversible Binding of DNA to an Inert Quaternary Ammonium Support.
Flood DT, Asai S, Zhang X, Wang J, Yoon L, Adams ZC, Dillingham BC, Sanchez BB, Vantourout JC, Flanagan ME, Piotrowski DW, Richardson P, Green SA, Shenvi RA, Chen JS, Baran PS, Dawson PE. Flood DT, et al. Among authors: chen js. J Am Chem Soc. 2019 Jun 26;141(25):9998-10006. doi: 10.1021/jacs.9b03774. Epub 2019 Jun 12. J Am Chem Soc. 2019. PMID: 31136164 Free PMC article.
RASS-Enabled S/P-C and S-N Bond Formation for DEL Synthesis.
Flood DT, Zhang X, Fu X, Zhao Z, Asai S, Sanchez BB, Sturgell EJ, Vantourout JC, Richardson P, Flanagan ME, Piotrowski DW, Kölmel DK, Wan J, Tsai MH, Chen JS, Baran PS, Dawson PE. Flood DT, et al. Among authors: chen js. Angew Chem Int Ed Engl. 2020 May 4;59(19):7377-7383. doi: 10.1002/anie.201915493. Epub 2020 Mar 11. Angew Chem Int Ed Engl. 2020. PMID: 32050046 Free PMC article.
Cycloisomerization of Olefins in Water.
Matos JLM, Green SA, Chun Y, Dang VQ, Dushin RG, Richardson P, Chen JS, Piotrowski DW, Paegel BM, Shenvi RA. Matos JLM, et al. Among authors: chen js. Angew Chem Int Ed Engl. 2020 Jul 27;59(31):12998-13003. doi: 10.1002/anie.202003948. Epub 2020 May 28. Angew Chem Int Ed Engl. 2020. PMID: 32285542 Free PMC article.
Direct Carbon Isotope Exchange through Decarboxylative Carboxylation.
Kingston C, Wallace MA, Allentoff AJ, deGruyter JN, Chen JS, Gong SX, Bonacorsi S Jr, Baran PS. Kingston C, et al. Among authors: chen js. J Am Chem Soc. 2019 Jan 16;141(2):774-779. doi: 10.1021/jacs.8b12035. Epub 2019 Jan 3. J Am Chem Soc. 2019. PMID: 30605319 Free PMC article.
A Radical Approach to Anionic Chemistry: Synthesis of Ketones, Alcohols, and Amines.
Ni S, Padial NM, Kingston C, Vantourout JC, Schmitt DC, Edwards JT, Kruszyk MM, Merchant RR, Mykhailiuk PK, Sanchez BB, Yang S, Perry MA, Gallego GM, Mousseau JJ, Collins MR, Cherney RJ, Lebed PS, Chen JS, Qin T, Baran PS. Ni S, et al. Among authors: chen js. J Am Chem Soc. 2019 Apr 24;141(16):6726-6739. doi: 10.1021/jacs.9b02238. Epub 2019 Apr 16. J Am Chem Soc. 2019. PMID: 30943023 Free PMC article.
2,945 results