Mali P - Search Results

1

Peptide-tiling screens of cancer drivers reveal oncogenic protein domains and associated peptide inhibitors.

Ford KM, Panwala R, Chen DH, Portell A, Palmer N, Mali P. Ford KM, et al. Among authors: mali p. Cell Syst. 2021 Jul 21;12(7):716-732.e7. doi: 10.1016/j.cels.2021.05.002. Epub 2021 May 28. Cell Syst. 2021. PMID: 34051140 Free PMC article.

2

Combinatorial CRISPR-Cas9 Metabolic Screens Reveal Critical Redox Control Points Dependent on the KEAP1-NRF2 Regulatory Axis.

Zhao D, Badur MG, Luebeck J, Magaña JH, Birmingham A, Sasik R, Ahn CS, Ideker T, Metallo CM, Mali P. Zhao D, et al. Among authors: mali p. Mol Cell. 2018 Feb 15;69(4):699-708.e7. doi: 10.1016/j.molcel.2018.01.017. Mol Cell. 2018. PMID: 29452643 Free PMC article.

3

Functional Genomics via CRISPR-Cas.

Ford K, McDonald D, Mali P. Ford K, et al. Among authors: mali p. J Mol Biol. 2019 Jan 4;431(1):48-65. doi: 10.1016/j.jmb.2018.06.034. Epub 2018 Jun 28. J Mol Biol. 2019. PMID: 29959923 Free PMC article. Review.

4

Mapping Cellular Reprogramming via Pooled Overexpression Screens with Paired Fitness and Single-Cell RNA-Sequencing Readout.

Parekh U, Wu Y, Zhao D, Worlikar A, Shah N, Zhang K, Mali P. Parekh U, et al. Among authors: mali p. Cell Syst. 2018 Nov 28;7(5):548-555.e8. doi: 10.1016/j.cels.2018.10.008. Epub 2018 Nov 14. Cell Syst. 2018. PMID: 30448000 Free PMC article.

5

Immune-orthogonal orthologues of AAV capsids and of Cas9 circumvent the immune response to the administration of gene therapy.

Moreno AM, Palmer N, Alemán F, Chen G, Pla A, Jiang N, Leong Chew W, Law M, Mali P. Moreno AM, et al. Among authors: mali p. Nat Biomed Eng. 2019 Oct;3(10):806-816. doi: 10.1038/s41551-019-0431-2. Epub 2019 Jul 22. Nat Biomed Eng. 2019. PMID: 31332341 Free PMC article.

6

Author Correction: Immune-orthogonal orthologues of AAV capsids and of Cas9 circumvent the immune response to the administration of gene therapy.

Moreno AM, Palmer N, Alemán F, Chen G, Pla A, Jiang N, Chew WL, Law M, Mali P. Moreno AM, et al. Among authors: mali p. Nat Biomed Eng. 2019 Oct;3(10):842. doi: 10.1038/s41551-019-0456-6. Nat Biomed Eng. 2019. PMID: 31455920

7

Translating CRISPR-Cas Therapeutics: Approaches and Challenges.

Tay LS, Palmer N, Panwala R, Chew WL, Mali P. Tay LS, et al. Among authors: mali p. CRISPR J. 2020 Aug;3(4):253-275. doi: 10.1089/crispr.2020.0025. CRISPR J. 2020. PMID: 32833535 Free PMC article. Review.

8

Synthetic Lethal Screens Reveal Cotargeting FAK and MEK as a Multimodal Precision Therapy for GNAQ-Driven Uveal Melanoma.

Paradis JS, Acosta M, Saddawi-Konefka R, Kishore A, Gomes F, Arang N, Tiago M, Coma S, Lubrano S, Wu X, Ford K, Day CP, Merlino G, Mali P, Pachter JA, Sato T, Aplin AE, Gutkind JS. Paradis JS, et al. Among authors: mali p. Clin Cancer Res. 2021 Jun 1;27(11):3190-3200. doi: 10.1158/1078-0432.CCR-20-3363. Epub 2021 Feb 10. Clin Cancer Res. 2021. PMID: 33568347 Free PMC article.

9

Long-lasting analgesia via targeted in situ repression of Na_V1.7 in mice.

Moreno AM, Alemán F, Catroli GF, Hunt M, Hu M, Dailamy A, Pla A, Woller SA, Palmer N, Parekh U, McDonald D, Roberts AJ, Goodwill V, Dryden I, Hevner RF, Delay L, Gonçalves Dos Santos G, Yaksh TL, Mali P. Moreno AM, et al. Among authors: mali p. Sci Transl Med. 2021 Mar 10;13(584):eaay9056. doi: 10.1126/scitranslmed.aay9056. Sci Transl Med. 2021. PMID: 33692134 Free PMC article.

10

Integrated genome and tissue engineering enables screening of cancer vulnerabilities in physiologically relevant perfusable ex vivo cultures.

Hu M, Lei XY, Larson JD, McAlonis M, Ford K, McDonald D, Mach K, Rusert JM, Wechsler-Reya RJ, Mali P. Hu M, et al. Among authors: mali p. Biomaterials. 2022 Jan;280:121276. doi: 10.1016/j.biomaterials.2021.121276. Epub 2021 Dec 2. Biomaterials. 2022. PMID: 34890975 Free PMC article.

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