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Nanoparticle-enabled innate immune stimulation activates endogenous tumor-infiltrating T cells with broad antigen specificities.
Yin Q, Yu W, Grzeskowiak CL, Li J, Huang H, Guo J, Chen L, Wang F, Zhao F, von Boehmer L, Metzner TJ, Leppert JT, Chien YH, Kuo CJ, Davis MM. Yin Q, et al. Among authors: chen l. Proc Natl Acad Sci U S A. 2021 May 25;118(21):e2016168118. doi: 10.1073/pnas.2016168118. Proc Natl Acad Sci U S A. 2021. PMID: 34021082 Free PMC article.
KIR+CD8+ T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19.
Li J, Zaslavsky M, Su Y, Guo J, Sikora MJ, van Unen V, Christophersen A, Chiou SH, Chen L, Li J, Ji X, Wilhelmy J, McSween AM, Palanski BA, Mallajosyula VVA, Bracey NA, Dhondalay GKR, Bhamidipati K, Pai J, Kipp LB, Dunn JE, Hauser SL, Oksenberg JR, Satpathy AT, Robinson WH, Dekker CL, Steinmetz LM, Khosla C, Utz PJ, Sollid LM, Chien YH, Heath JR, Fernandez-Becker NQ, Nadeau KC, Saligrama N, Davis MM. Li J, et al. Among authors: chen l. Science. 2022 Apr 15;376(6590):eabi9591. doi: 10.1126/science.abi9591. Epub 2022 Apr 15. Science. 2022. PMID: 35258337 Free PMC article.
Evolution and modulation of antigen-specific T cell responses in melanoma patients.
Huuhtanen J, Chen L, Jokinen E, Kasanen H, Lönnberg T, Kreutzman A, Peltola K, Hernberg M, Wang C, Yee C, Lähdesmäki H, Davis MM, Mustjoki S. Huuhtanen J, et al. Among authors: chen l. Nat Commun. 2022 Oct 11;13(1):5988. doi: 10.1038/s41467-022-33720-z. Nat Commun. 2022. PMID: 36220826 Free PMC article.
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