Miao YR - Search Results

1

Neutralization of PD-L2 is Essential for Overcoming Immune Checkpoint Blockade Resistance in Ovarian Cancer.

Miao YR, Thakkar KN, Qian J, Kariolis MS, Huang W, Nandagopal S, Yang TTC, Diep AN, Cherf GM, Xu Y, Moon EJ, Xiao Y, Alemany H, Li T, Yu W, Wei B, Rankin EB, Giaccia AJ. Miao YR, et al. Clin Cancer Res. 2021 Aug 1;27(15):4435-4448. doi: 10.1158/1078-0432.CCR-20-0482. Epub 2021 May 19. Clin Cancer Res. 2021. PMID: 34011561 Free PMC article.

2

PHD inhibition mitigates and protects against radiation-induced gastrointestinal toxicity via HIF2.

Taniguchi CM, Miao YR, Diep AN, Wu C, Rankin EB, Atwood TF, Xing L, Giaccia AJ. Taniguchi CM, et al. Among authors: miao yr. Sci Transl Med. 2014 May 14;6(236):236ra64. doi: 10.1126/scitranslmed.3008523. Sci Transl Med. 2014. PMID: 24828078 Free PMC article.

3

Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET.

Rankin EB, Fuh KC, Castellini L, Viswanathan K, Finger EC, Diep AN, LaGory EL, Kariolis MS, Chan A, Lindgren D, Axelson H, Miao YR, Krieg AJ, Giaccia AJ. Rankin EB, et al. Among authors: miao yr. Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13373-8. doi: 10.1073/pnas.1404848111. Epub 2014 Sep 3. Proc Natl Acad Sci U S A. 2014. PMID: 25187556 Free PMC article.

4

An engineered Axl 'decoy receptor' effectively silences the Gas6-Axl signaling axis.

Kariolis MS, Miao YR, Jones DS 2nd, Kapur S, Mathews II, Giaccia AJ, Cochran JR. Kariolis MS, et al. Among authors: miao yr. Nat Chem Biol. 2014 Nov;10(11):977-83. doi: 10.1038/nchembio.1636. Epub 2014 Sep 21. Nat Chem Biol. 2014. PMID: 25242553 Free PMC article.

5

Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies.

Kariolis MS, Miao YR, Diep A, Nash SE, Olcina MM, Jiang D, Jones DS 2nd, Kapur S, Mathews II, Koong AC, Rankin EB, Cochran JR, Giaccia AJ. Kariolis MS, et al. Among authors: miao yr. J Clin Invest. 2017 Jan 3;127(1):183-198. doi: 10.1172/JCI85610. Epub 2016 Nov 28. J Clin Invest. 2017. PMID: 27893463 Free PMC article.

6

S100A10 Is a Critical Mediator of GAS6/AXL-Induced Angiogenesis in Renal Cell Carcinoma.

Xiao Y, Zhao H, Tian L, Nolley R, Diep AN, Ernst A, Fuh KC, Miao YR, von Eyben R, Leppert JT, Brooks JD, Peehl DM, Giaccia AJ, Rankin EB. Xiao Y, et al. Among authors: miao yr. Cancer Res. 2019 Nov 15;79(22):5758-5768. doi: 10.1158/0008-5472.CAN-19-1366. Epub 2019 Oct 4. Cancer Res. 2019. PMID: 31585940 Free PMC article.

7

The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling.

Moon EJ, Mello SS, Li CG, Chi JT, Thakkar K, Kirkland JG, Lagory EL, Lee IJ, Diep AN, Miao Y, Rafat M, Vilalta M, Castellini L, Krieg AJ, Graves EE, Attardi LD, Giaccia AJ. Moon EJ, et al. Nat Commun. 2021 Jul 14;12(1):4308. doi: 10.1038/s41467-021-24631-6. Nat Commun. 2021. PMID: 34262028 Free PMC article.

8

Developing high-affinity decoy receptors to treat multiple myeloma and diffuse large B cell lymphoma.

Miao YR, Thakkar K, Cenik C, Jiang D, Mizuno K, Jia C, Li CG, Zhao H, Diep A, Xu Y, Zhang XE, Yang TTC, Liedtke M, Abidi P, Leung WS, Koong AC, Giaccia AJ. Miao YR, et al. J Exp Med. 2022 Sep 5;219(9):e20220214. doi: 10.1084/jem.20220214. Epub 2022 Jul 26. J Exp Med. 2022. PMID: 35881112 Free PMC article.

9

Therapeutic targeting of the functionally elusive TAM receptor family.

Miao YR, Rankin EB, Giaccia AJ. Miao YR, et al. Nat Rev Drug Discov. 2024 Mar;23(3):201-217. doi: 10.1038/s41573-023-00846-8. Epub 2023 Dec 13. Nat Rev Drug Discov. 2024. PMID: 38092952 Review.

10

Induction of LIFR confers a dormancy phenotype in breast cancer cells disseminated to the bone marrow.

Johnson RW, Finger EC, Olcina MM, Vilalta M, Aguilera T, Miao Y, Merkel AR, Johnson JR, Sterling JA, Wu JY, Giaccia AJ. Johnson RW, et al. Nat Cell Biol. 2016 Oct;18(10):1078-1089. doi: 10.1038/ncb3408. Epub 2016 Sep 19. Nat Cell Biol. 2016. PMID: 27642788 Free PMC article.

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