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The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake.
de Mingo Pulido Á, Hänggi K, Celias DP, Gardner A, Li J, Batista-Bittencourt B, Mohamed E, Trillo-Tinoco J, Osunmakinde O, Peña R, Onimus A, Kaisho T, Kaufmann J, McEachern K, Soliman H, Luca VC, Rodriguez PC, Yu X, Ruffell B. de Mingo Pulido Á, et al. Among authors: gardner a. Immunity. 2021 Jun 8;54(6):1154-1167.e7. doi: 10.1016/j.immuni.2021.04.019. Epub 2021 May 11. Immunity. 2021. PMID: 33979578 Free PMC article.
Dendritic Cells and Cancer Immunity.
Gardner A, Ruffell B. Gardner A, et al. Trends Immunol. 2016 Dec;37(12):855-865. doi: 10.1016/j.it.2016.09.006. Epub 2016 Oct 25. Trends Immunol. 2016. PMID: 27793569 Free PMC article. Review.
Reducing interferon'ce in stem cells.
Gardner A, Ruffell B. Gardner A, et al. Nat Cell Biol. 2017 May 31;19(6):597-599. doi: 10.1038/ncb3544. Nat Cell Biol. 2017. PMID: 28561058
moDCs, Less Problems.
Gardner A, Ruffell B. Gardner A, et al. Immunity. 2018 Jan 16;48(1):6-8. doi: 10.1016/j.immuni.2017.12.017. Immunity. 2018. PMID: 29343441 Free article.
Dendritic Cells and Their Role in Immunotherapy.
Gardner A, de Mingo Pulido Á, Ruffell B. Gardner A, et al. Front Immunol. 2020 May 21;11:924. doi: 10.3389/fimmu.2020.00924. eCollection 2020. Front Immunol. 2020. PMID: 32508825 Free PMC article. Review.
Fucosylation of HLA-DRB1 regulates CD4+ T cell-mediated anti-melanoma immunity and enhances immunotherapy efficacy.
Lester DK, Burton C, Gardner A, Innamarato P, Kodumudi K, Liu Q, Adhikari E, Ming Q, Williamson DB, Frederick DT, Sharova T, White MG, Markowitz J, Cao B, Nguyen J, Johnson J, Beatty M, Mockabee-Macias A, Mercurio M, Watson G, Chen PL, McCarthy S, MoranSegura C, Messina J, Thomas KL, Darville L, Izumi V, Koomen JM, Pilon-Thomas SA, Ruffell B, Luca VC, Haltiwanger RS, Wang X, Wargo JA, Boland GM, Lau EK. Lester DK, et al. Among authors: gardner a. Nat Cancer. 2023 Feb;4(2):222-239. doi: 10.1038/s43018-022-00506-7. Epub 2023 Jan 23. Nat Cancer. 2023. PMID: 36690875 Free PMC article.
1,911 results