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Synthetic lethal targeting of DNA double-strand break repair deficient cells by human apurinic/apyrimidinic endonuclease inhibitors.
Sultana R, McNeill DR, Abbotts R, Mohammed MZ, Zdzienicka MZ, Qutob H, Seedhouse C, Laughton CA, Fischer PM, Patel PM, Wilson DM 3rd, Madhusudan S. Sultana R, et al. Among authors: madhusudan s. Int J Cancer. 2012 Nov 15;131(10):2433-44. doi: 10.1002/ijc.27512. Epub 2012 Mar 28. Int J Cancer. 2012. PMID: 22377908 Free PMC article.
Targeting XRCC1 deficiency in breast cancer for personalized therapy.
Sultana R, Abdel-Fatah T, Abbotts R, Hawkes C, Albarakati N, Seedhouse C, Ball G, Chan S, Rakha EA, Ellis IO, Madhusudan S. Sultana R, et al. Among authors: madhusudan s. Cancer Res. 2013 Mar 1;73(5):1621-34. doi: 10.1158/0008-5472.CAN-12-2929. Epub 2012 Dec 19. Cancer Res. 2013. PMID: 23253910
SUMOylation proteins in breast cancer.
Alshareeda AT, Negm OH, Green AR, Nolan C, Tighe P, Albarakati N, Sultana R, Madhusudan S, Ellis IO, Rakha EA. Alshareeda AT, et al. Among authors: madhusudan s. Breast Cancer Res Treat. 2014 Apr;144(3):519-30. doi: 10.1007/s10549-014-2897-7. Epub 2014 Mar 1. Breast Cancer Res Treat. 2014. PMID: 24584753
Targeting human apurinic/apyrimidinic endonuclease 1 (APE1) in phosphatase and tensin homolog (PTEN) deficient melanoma cells for personalized therapy.
Abbotts R, Jewell R, Nsengimana J, Maloney DJ, Simeonov A, Seedhouse C, Elliott F, Laye J, Walker C, Jadhav A, Grabowska A, Ball G, Patel PM, Newton-Bishop J, Wilson DM 3rd, Madhusudan S. Abbotts R, et al. Among authors: madhusudan s. Oncotarget. 2014 May 30;5(10):3273-86. doi: 10.18632/oncotarget.1926. Oncotarget. 2014. PMID: 24830350 Free PMC article.
Genomic and protein expression analysis reveals flap endonuclease 1 (FEN1) as a key biomarker in breast and ovarian cancer.
Abdel-Fatah TM, Russell R, Albarakati N, Maloney DJ, Dorjsuren D, Rueda OM, Moseley P, Mohan V, Sun H, Abbotts R, Mukherjee A, Agarwal D, Illuzzi JL, Jadhav A, Simeonov A, Ball G, Chan S, Caldas C, Ellis IO, Wilson DM 3rd, Madhusudan S. Abdel-Fatah TM, et al. Among authors: madhusudan s. Mol Oncol. 2014 Oct;8(7):1326-38. doi: 10.1016/j.molonc.2014.04.009. Epub 2014 May 13. Mol Oncol. 2014. PMID: 24880630 Free PMC article.
Adverse prognostic and predictive significance of low DNA-dependent protein kinase catalytic subunit (DNA-PKcs) expression in early-stage breast cancers.
Abdel-Fatah T, Arora A, Agarwal D, Moseley P, Perry C, Thompson N, Green AR, Rakha E, Chan S, Ball G, Ellis IO, Madhusudan S. Abdel-Fatah T, et al. Among authors: madhusudan s. Breast Cancer Res Treat. 2014 Jul;146(2):309-20. doi: 10.1007/s10549-014-3035-2. Epub 2014 Jun 28. Breast Cancer Res Treat. 2014. PMID: 24972688
183 results