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New framework for a non-animal approach adequately assures the safety of cosmetic ingredients - A case study on caffeine.
Bury D, Alexander-White C, Clewell HJ 3rd, Cronin M, Desprez B, Detroyer A, Efremenko A, Firman J, Hack E, Hewitt NJ, Kenna G, Klaric M, Lester C, Mahony C, Ouedraogo G, Paini A, Schepky A; Cosmetics Europe. Bury D, et al. Among authors: mahony c. Regul Toxicol Pharmacol. 2021 Jul;123:104931. doi: 10.1016/j.yrtph.2021.104931. Epub 2021 Apr 24. Regul Toxicol Pharmacol. 2021. PMID: 33905778 Free article.
Case studies to test: A framework for using structural, reactivity, metabolic and physicochemical similarity to evaluate the suitability of analogs for SAR-based toxicological assessments.
Blackburn K, Bjerke D, Daston G, Felter S, Mahony C, Naciff J, Robison S, Wu S. Blackburn K, et al. Among authors: mahony c. Regul Toxicol Pharmacol. 2011 Jun;60(1):120-35. doi: 10.1016/j.yrtph.2011.03.002. Epub 2011 Mar 21. Regul Toxicol Pharmacol. 2011. PMID: 21420459
The SEURAT-1 approach towards animal free human safety assessment.
Gocht T, Berggren E, Ahr HJ, Cotgreave I, Cronin MT, Daston G, Hardy B, Heinzle E, Hescheler J, Knight DJ, Mahony C, Peschanski M, Schwarz M, Thomas RS, Verfaillie C, White A, Whelan M. Gocht T, et al. Among authors: mahony c. ALTEX. 2015;32(1):9-24. doi: 10.14573/altex.1408041. Epub 2014 Nov 5. ALTEX. 2015. PMID: 25372315 Free article.
Chemical Safety Assessment Using Read-Across: Assessing the Use of Novel Testing Methods to Strengthen the Evidence Base for Decision Making.
Berggren E, Amcoff P, Benigni R, Blackburn K, Carney E, Cronin M, Deluyker H, Gautier F, Judson RS, Kass GE, Keller D, Knight D, Lilienblum W, Mahony C, Rusyn I, Schultz T, Schwarz M, Schüürmann G, White A, Burton J, Lostia AM, Munn S, Worth A. Berggren E, et al. Among authors: mahony c. Environ Health Perspect. 2015 Dec;123(12):1232-40. doi: 10.1289/ehp.1409342. Epub 2015 May 8. Environ Health Perspect. 2015. PMID: 25956009 Free PMC article. Review.
A strategy for structuring and reporting a read-across prediction of toxicity.
Schultz TW, Amcoff P, Berggren E, Gautier F, Klaric M, Knight DJ, Mahony C, Schwarz M, White A, Cronin MT. Schultz TW, et al. Among authors: mahony c. Regul Toxicol Pharmacol. 2015 Aug;72(3):586-601. doi: 10.1016/j.yrtph.2015.05.016. Epub 2015 May 21. Regul Toxicol Pharmacol. 2015. PMID: 26003513 Free article.
A strategy for systemic toxicity assessment based on non-animal approaches: The Cosmetics Europe Long Range Science Strategy programme.
Desprez B, Dent M, Keller D, Klaric M, Ouédraogo G, Cubberley R, Duplan H, Eilstein J, Ellison C, Grégoire S, Hewitt NJ, Jacques-Jamin C, Lange D, Roe A, Rothe H, Blaauboer BJ, Schepky A, Mahony C. Desprez B, et al. Among authors: mahony c. Toxicol In Vitro. 2018 Aug;50:137-146. doi: 10.1016/j.tiv.2018.02.017. Epub 2018 Mar 2. Toxicol In Vitro. 2018. PMID: 29499337 Review.
One science-driven approach for the regulatory implementation of alternative methods: A multi-sector perspective.
Dal Negro G, Eskes C, Belz S, Bertein C, Chlebus M, Corvaro M, Corvi R, Dhalluin S, Halder M, Harvey J, Hermann M, Hoffmann-Dörr S, Kilian K, Lambrigts D, Laroche C, Louhimies S, Mahony C, Manou I, McNamee P, Prieto P, Reid K, Roggen E, Schutte K, Stirling C, Uhlrich S, Weissenhorn R, Whelan M. Dal Negro G, et al. Among authors: mahony c. Regul Toxicol Pharmacol. 2018 Nov;99:33-49. doi: 10.1016/j.yrtph.2018.08.002. Epub 2018 Aug 8. Regul Toxicol Pharmacol. 2018. PMID: 30098372 Free article.
233 results