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Specific Protein 1 and p53 Interplay Modulates the Expression of the KCTD-Containing Cullin3 Adaptor Suppressor of Hedgehog 2.
Angrisani A, Di Fiore A, Di Trani CA, Fonte S, Petroni M, Lospinoso Severini L, Bordin F, Belloni L, Ferretti E, Canettieri G, Moretti M, De Smaele E. Angrisani A, et al. Among authors: moretti m. Front Cell Dev Biol. 2021 Apr 8;9:638508. doi: 10.3389/fcell.2021.638508. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 33898425 Free PMC article.
An integrated approach identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated genes in developing cerebellum and medulloblastoma.
De Smaele E, Fragomeli C, Ferretti E, Pelloni M, Po A, Canettieri G, Coni S, Di Marcotullio L, Greco A, Moretti M, Di Rocco C, Pazzaglia S, Maroder M, Screpanti I, Giannini G, Gulino A. De Smaele E, et al. Among authors: moretti m. Neoplasia. 2008 Jan;10(1):89-98. doi: 10.1593/neo.07891. Neoplasia. 2008. PMID: 18231642 Free PMC article.
Identification and characterization of KCASH2 and KCASH3, 2 novel Cullin3 adaptors suppressing histone deacetylase and Hedgehog activity in medulloblastoma.
De Smaele E, Di Marcotullio L, Moretti M, Pelloni M, Occhione MA, Infante P, Cucchi D, Greco A, Pietrosanti L, Todorovic J, Coni S, Canettieri G, Ferretti E, Bei R, Maroder M, Screpanti I, Gulino A. De Smaele E, et al. Among authors: moretti m. Neoplasia. 2011 Apr;13(4):374-85. doi: 10.1593/neo.101630. Neoplasia. 2011. PMID: 21472142 Free PMC article.
Foxm1 controls a pro-stemness microRNA network in neural stem cells.
Besharat ZM, Abballe L, Cicconardi F, Bhutkar A, Grassi L, Le Pera L, Moretti M, Chinappi M, D'Andrea D, Mastronuzzi A, Ianari A, Vacca A, De Smaele E, Locatelli F, Po A, Miele E, Ferretti E. Besharat ZM, et al. Among authors: moretti m. Sci Rep. 2018 Feb 23;8(1):3523. doi: 10.1038/s41598-018-21876-y. Sci Rep. 2018. PMID: 29476172 Free PMC article.
ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP.
Bufalieri F, Infante P, Bernardi F, Caimano M, Romania P, Moretti M, Lospinoso Severini L, Talbot J, Melaiu O, Tanori M, Di Magno L, Bellavia D, Capalbo C, Puget S, De Smaele E, Canettieri G, Guardavaccaro D, Busino L, Peschiaroli A, Pazzaglia S, Giannini G, Melino G, Locatelli F, Gulino A, Ayrault O, Fruci D, Di Marcotullio L. Bufalieri F, et al. Among authors: moretti m. Nat Commun. 2019 Jul 24;10(1):3304. doi: 10.1038/s41467-019-11093-0. Nat Commun. 2019. PMID: 31341163 Free PMC article.
A Smo/Gli Multitarget Hedgehog Pathway Inhibitor Impairs Tumor Growth.
Lospinoso Severini L, Quaglio D, Basili I, Ghirga F, Bufalieri F, Caimano M, Balducci S, Moretti M, Romeo I, Loricchio E, Maroder M, Botta B, Mori M, Infante P, Di Marcotullio L. Lospinoso Severini L, et al. Among authors: moretti m. Cancers (Basel). 2019 Oct 9;11(10):1518. doi: 10.3390/cancers11101518. Cancers (Basel). 2019. PMID: 31601026 Free PMC article.
KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2.
Spiombi E, Angrisani A, Fonte S, De Feudis G, Fabretti F, Cucchi D, Izzo M, Infante P, Miele E, Po A, Di Magno L, Magliozzi R, Guardavaccaro D, Maroder M, Canettieri G, Giannini G, Ferretti E, Gulino A, Di Marcotullio L, Moretti M, De Smaele E. Spiombi E, et al. Among authors: moretti m. Oncogenesis. 2019 Nov 4;8(11):64. doi: 10.1038/s41389-019-0175-6. Oncogenesis. 2019. PMID: 31685809 Free PMC article.
1,396 results