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Specific Protein 1 and p53 Interplay Modulates the Expression of the KCTD-Containing Cullin3 Adaptor Suppressor of Hedgehog 2.
Angrisani A, Di Fiore A, Di Trani CA, Fonte S, Petroni M, Lospinoso Severini L, Bordin F, Belloni L, Ferretti E, Canettieri G, Moretti M, De Smaele E. Angrisani A, et al. Among authors: canettieri g. Front Cell Dev Biol. 2021 Apr 8;9:638508. doi: 10.3389/fcell.2021.638508. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 33898425 Free PMC article.
An integrated approach identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated genes in developing cerebellum and medulloblastoma.
De Smaele E, Fragomeli C, Ferretti E, Pelloni M, Po A, Canettieri G, Coni S, Di Marcotullio L, Greco A, Moretti M, Di Rocco C, Pazzaglia S, Maroder M, Screpanti I, Giannini G, Gulino A. De Smaele E, et al. Among authors: canettieri g. Neoplasia. 2008 Jan;10(1):89-98. doi: 10.1593/neo.07891. Neoplasia. 2008. PMID: 18231642 Free PMC article.
Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation.
Canettieri G, Di Marcotullio L, Greco A, Coni S, Antonucci L, Infante P, Pietrosanti L, De Smaele E, Ferretti E, Miele E, Pelloni M, De Simone G, Pedone EM, Gallinari P, Giorgi A, Steinkühler C, Vitagliano L, Pedone C, Schinin ME, Screpanti I, Gulino A. Canettieri G, et al. Nat Cell Biol. 2010 Feb;12(2):132-42. doi: 10.1038/ncb2013. Epub 2010 Jan 17. Nat Cell Biol. 2010. PMID: 20081843
Hedgehog controls neural stem cells through p53-independent regulation of Nanog.
Po A, Ferretti E, Miele E, De Smaele E, Paganelli A, Canettieri G, Coni S, Di Marcotullio L, Biffoni M, Massimi L, Di Rocco C, Screpanti I, Gulino A. Po A, et al. Among authors: canettieri g. EMBO J. 2010 Aug 4;29(15):2646-58. doi: 10.1038/emboj.2010.131. Epub 2010 Jun 25. EMBO J. 2010. PMID: 20581804 Free PMC article.
Identification and characterization of KCASH2 and KCASH3, 2 novel Cullin3 adaptors suppressing histone deacetylase and Hedgehog activity in medulloblastoma.
De Smaele E, Di Marcotullio L, Moretti M, Pelloni M, Occhione MA, Infante P, Cucchi D, Greco A, Pietrosanti L, Todorovic J, Coni S, Canettieri G, Ferretti E, Bei R, Maroder M, Screpanti I, Gulino A. De Smaele E, et al. Among authors: canettieri g. Neoplasia. 2011 Apr;13(4):374-85. doi: 10.1593/neo.101630. Neoplasia. 2011. PMID: 21472142 Free PMC article.
Hedgehog/Gli control by ubiquitination/acetylation interplay.
Gulino A, Di Marcotullio L, Canettieri G, De Smaele E, Screpanti I. Gulino A, et al. Among authors: canettieri g. Vitam Horm. 2012;88:211-27. doi: 10.1016/B978-0-12-394622-5.00009-2. Vitam Horm. 2012. PMID: 22391305 Review.
PCAF ubiquitin ligase activity inhibits Hedgehog/Gli1 signaling in p53-dependent response to genotoxic stress.
Mazzà D, Infante P, Colicchia V, Greco A, Alfonsi R, Siler M, Antonucci L, Po A, De Smaele E, Ferretti E, Capalbo C, Bellavia D, Canettieri G, Giannini G, Screpanti I, Gulino A, Di Marcotullio L. Mazzà D, et al. Among authors: canettieri g. Cell Death Differ. 2013 Dec;20(12):1688-97. doi: 10.1038/cdd.2013.120. Epub 2013 Sep 6. Cell Death Differ. 2013. PMID: 24013724 Free PMC article.
Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors.
Infante P, Mori M, Alfonsi R, Ghirga F, Aiello F, Toscano S, Ingallina C, Siler M, Cucchi D, Po A, Miele E, D'Amico D, Canettieri G, De Smaele E, Ferretti E, Screpanti I, Uccello Barretta G, Botta M, Botta B, Gulino A, Di Marcotullio L. Infante P, et al. Among authors: canettieri g. EMBO J. 2015 Jan 13;34(2):200-17. doi: 10.15252/embj.201489213. Epub 2014 Dec 4. EMBO J. 2015. PMID: 25476449 Free PMC article.
89 results