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Safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2: a randomised, double-blind, placebo-controlled, phase 1 trial.
Lancet Infect Dis. 2021 Oct;21(10):1383-1394. doi: 10.1016/S1473-3099(21)00200-0. Epub 2021 Apr 19.
Lancet Infect Dis. 2021.
PMID: 33887208
Free PMC article.
Clinical Trial.
Safety, tolerability, pharmacokinetics, and immunogenicity of a human monoclonal antibody targeting the G glycoprotein of henipaviruses in healthy adults: a first-in-human, randomised, controlled, phase 1 study.
Playford EG, Munro T, Mahler SM, Elliott S, Gerometta M, Hoger KL, Jones ML, Griffin P, Lynch KD, Carroll H, El Saadi D, Gilmour ME, Hughes B, Hughes K, Huang E, de Bakker C, Klein R, Scher MG, Smith IL, Wang LF, Lambert SB, Dimitrov DS, Gray PP, Broder CC.
Playford EG, et al. Among authors: hoger kl.
Lancet Infect Dis. 2020 Apr;20(4):445-454. doi: 10.1016/S1473-3099(19)30634-6. Epub 2020 Feb 3.
Lancet Infect Dis. 2020.
PMID: 32027842
Clinical Trial.
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Preclinical development of a molecular clamp-stabilised subunit vaccine for severe acute respiratory syndrome coronavirus 2.
Watterson D, Wijesundara DK, Modhiran N, Mordant FL, Li Z, Avumegah MS, McMillan CL, Lackenby J, Guilfoyle K, van Amerongen G, Stittelaar K, Cheung ST, Bibby S, Daleris M, Hoger K, Gillard M, Radunz E, Jones ML, Hughes K, Hughes B, Goh J, Edwards D, Scoble J, Pearce L, Kowalczyk L, Phan T, La M, Lu L, Pham T, Zhou Q, Brockman DA, Morgan SJ, Lau C, Tran MH, Tapley P, Villalón-Letelier F, Barnes J, Young A, Jaberolansar N, Scott CA, Isaacs A, Amarilla AA, Khromykh AA, van den Brand JM, Reading PC, Ranasinghe C, Subbarao K, Munro TP, Young PR, Chappell KJ.
Watterson D, et al. Among authors: hoger k.
Clin Transl Immunology. 2021 Apr 5;10(4):e1269. doi: 10.1002/cti2.1269. eCollection 2021.
Clin Transl Immunology. 2021.
PMID: 33841880
Free PMC article.
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IgG1 adsorption to siliconized glass vials-influence of pH, ionic strength, and nonionic surfactants.
Höger K, Mathes J, Frieß W.
Höger K, et al.
J Pharm Sci. 2015 Jan;104(1):34-43. doi: 10.1002/jps.24239. Epub 2014 Nov 12.
J Pharm Sci. 2015.
PMID: 25394280
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Polyglycerol coatings of glass vials for protein resistance.
Höger K, Becherer T, Qiang W, Haag R, Friess W, Küchler S.
Höger K, et al.
Eur J Pharm Biopharm. 2013 Nov;85(3 Pt A):756-64. doi: 10.1016/j.ejpb.2013.04.005. Epub 2013 Apr 25.
Eur J Pharm Biopharm. 2013.
PMID: 23624376
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