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Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism.
Fachi JL, Felipe JS, Pral LP, da Silva BK, Corrêa RO, de Andrade MCP, da Fonseca DM, Basso PJ, Câmara NOS, de Sales E Souza ÉL, Dos Santos Martins F, Guima SES, Thomas AM, Setubal JC, Magalhães YT, Forti FL, Candreva T, Rodrigues HG, de Jesus MB, Consonni SR, Farias ADS, Varga-Weisz P, Vinolo MAR. Fachi JL, et al. Cell Rep. 2019 Apr 16;27(3):750-761.e7. doi: 10.1016/j.celrep.2019.03.054. Cell Rep. 2019. PMID: 30995474 Free article.
Microbiota-derived acetate protects against respiratory syncytial virus infection through a GPR43-type 1 interferon response.
Antunes KH, Fachi JL, de Paula R, da Silva EF, Pral LP, Dos Santos AÁ, Dias GBM, Vargas JE, Puga R, Mayer FQ, Maito F, Zárate-Bladés CR, Ajami NJ, Sant'Ana MR, Candreva T, Rodrigues HG, Schmiele M, Silva Clerici MTP, Proença-Modena JL, Vieira AT, Mackay CR, Mansur D, Caballero MT, Marzec J, Li J, Wang X, Bell D, Polack FP, Kleeberger SR, Stein RT, Vinolo MAR, de Souza APD. Antunes KH, et al. Among authors: fachi jl. Nat Commun. 2019 Jul 22;10(1):3273. doi: 10.1038/s41467-019-11152-6. Nat Commun. 2019. PMID: 31332169 Free PMC article.
ILC2s are the predominant source of intestinal ILC-derived IL-10.
Bando JK, Gilfillan S, Di Luccia B, Fachi JL, Sécca C, Cella M, Colonna M. Bando JK, et al. Among authors: fachi jl. J Exp Med. 2020 Feb 3;217(2):e20191520. doi: 10.1084/jem.20191520. J Exp Med. 2020. PMID: 31699824 Free PMC article.
Acetate coordinates neutrophil and ILC3 responses against C. difficile through FFAR2.
Fachi JL, Sécca C, Rodrigues PB, Mato FCP, Di Luccia B, Felipe JS, Pral LP, Rungue M, Rocha VM, Sato FT, Sampaio U, Clerici MTPS, Rodrigues HG, Câmara NOS, Consonni SR, Vieira AT, Oliveira SC, Mackay CR, Layden BT, Bortoluci KR, Colonna M, Vinolo MAR. Fachi JL, et al. J Exp Med. 2020 Mar 2;217(3):jem.20190489. doi: 10.1084/jem.20190489. J Exp Med. 2020. PMID: 31876919 Free PMC article.
Hypoxia enhances ILC3 responses through HIF-1α-dependent mechanism.
Fachi JL, Pral LP, Dos Santos JAC, Codo AC, de Oliveira S, Felipe JS, Zambom FFF, Câmara NOS, Vieira PMMM, Colonna M, Vinolo MAR. Fachi JL, et al. Mucosal Immunol. 2021 Jul;14(4):828-841. doi: 10.1038/s41385-020-00371-6. Epub 2021 Jan 14. Mucosal Immunol. 2021. PMID: 33446906 Free PMC article.
30 results