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Esters of Pyrazinoic Acid Are Active against Pyrazinamide-Resistant Strains of Mycobacterium tuberculosis and Other Naturally Resistant Mycobacteria In Vitro and Ex Vivo within Macrophages.
Pires D, Valente E, Simões MF, Carmo N, Testa B, Constantino L, Anes E. Pires D, et al. Among authors: valente e. Antimicrob Agents Chemother. 2015 Dec;59(12):7693-9. doi: 10.1128/AAC.00936-15. Epub 2015 Oct 5. Antimicrob Agents Chemother. 2015. PMID: 26438493 Free PMC article.
In previous work, we have shown that POA esters and amides synthesized in our laboratory were stable in plasma (M. F. Simoes, E. Valente, M. J. Gomez, E. Anes, and L. Constantino, Eur J Pharm Sci 37:257-263, 2009, http://dx.doi.org/10.1016/j.ejps.2009.02.012) …
In previous work, we have shown that POA esters and amides synthesized in our laboratory were stable in plasma (M. F. Simoes, E. V …
Benzoic Acid Derivatives as Prodrugs for the Treatment of Tuberculosis.
Pais JP, Magalhães M, Antoniuk O, Barbosa I, Freire R, Pires D, Valente E, Testa B, Anes E, Constantino L. Pais JP, et al. Among authors: valente e. Pharmaceuticals (Basel). 2022 Sep 7;15(9):1118. doi: 10.3390/ph15091118. Pharmaceuticals (Basel). 2022. PMID: 36145340 Free PMC article.
Structure of warfarin in solution.
Valente EJ, Lingafelter EC, Porter WR, Trager WF. Valente EJ, et al. J Med Chem. 1977 Nov;20(11):1489-93. doi: 10.1021/jm00221a025. J Med Chem. 1977. PMID: 915911
605 results