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Influence of the protein kinase C activator phorbol myristate acetate on the intracellular activity of antibiotics against hemin- and menadione-auxotrophic small-colony variant mutants of Staphylococcus aureus and their wild-type parental strain in human THP-1 cells.
Garcia LG, Lemaire S, Kahl BC, Becker K, Proctor RA, Tulkens PM, Van Bambeke F. Garcia LG, et al. Among authors: kahl bc. Antimicrob Agents Chemother. 2012 Dec;56(12):6166-74. doi: 10.1128/AAC.01031-12. Epub 2012 Sep 17. Antimicrob Agents Chemother. 2012. PMID: 22985883 Free PMC article.
Intracellular forms of menadione-dependent small-colony variants of methicillin-resistant Staphylococcus aureus are hypersusceptible to β-lactams in a THP-1 cell model due to cooperation between vacuolar acidic pH and oxidant species.
Garcia LG, Lemaire S, Kahl BC, Becker K, Proctor RA, Tulkens PM, Van Bambeke F. Garcia LG, et al. Among authors: kahl bc. J Antimicrob Chemother. 2012 Dec;67(12):2873-81. doi: 10.1093/jac/dks325. Epub 2012 Sep 21. J Antimicrob Chemother. 2012. PMID: 23002174
104 results