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Malaria primes the innate immune response due to interferon-gamma induced enhancement of toll-like receptor expression and function.
Franklin BS, Parroche P, Ataíde MA, Lauw F, Ropert C, de Oliveira RB, Pereira D, Tada MS, Nogueira P, da Silva LH, Bjorkbacka H, Golenbock DT, Gazzinelli RT. Franklin BS, et al. Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5789-94. doi: 10.1073/pnas.0809742106. Epub 2009 Mar 18. Proc Natl Acad Sci U S A. 2009. PMID: 19297619 Free PMC article.
Augmented plasma microparticles during acute Plasmodium vivax infection.
Campos FM, Franklin BS, Teixeira-Carvalho A, Filho AL, de Paula SC, Fontes CJ, Brito CF, Carvalho LH. Campos FM, et al. Among authors: franklin bs. Malar J. 2010 Nov 16;9:327. doi: 10.1186/1475-2875-9-327. Malar J. 2010. PMID: 21080932 Free PMC article.
Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection.
Ataide MA, Andrade WA, Zamboni DS, Wang D, Souza Mdo C, Franklin BS, Elian S, Martins FS, Pereira D, Reed G, Fitzgerald KA, Golenbock DT, Gazzinelli RT. Ataide MA, et al. Among authors: franklin bs. PLoS Pathog. 2014 Jan;10(1):e1003885. doi: 10.1371/journal.ppat.1003885. Epub 2014 Jan 16. PLoS Pathog. 2014. PMID: 24453977 Free PMC article. Clinical Trial.
Platelets Fuel the Inflammasome Activation of Innate Immune Cells.
Rolfes V, Ribeiro LS, Hawwari I, Böttcher L, Rosero N, Maasewerd S, Santos MLS, Próchnicki T, Silva CMS, Wanderley CWS, Rothe M, Schmidt SV, Stunden HJ, Bertheloot D, Rivas MN, Fontes CJ, Carvalho LH, Cunha FQ, Latz E, Arditi M, Franklin BS. Rolfes V, et al. Among authors: franklin bs. Cell Rep. 2020 May 12;31(6):107615. doi: 10.1016/j.celrep.2020.107615. Cell Rep. 2020. PMID: 32402278 Free PMC article.
Nanobodies dismantle post-pyroptotic ASC specks and counteract inflammation in vivo.
Bertheloot D, Wanderley CW, Schneider AH, Schiffelers LD, Wuerth JD, Tödtmann JM, Maasewerd S, Hawwari I, Duthie F, Rohland C, Ribeiro LS, Jenster LM, Rosero N, Tesfamariam YM, Cunha FQ, Schmidt FI, Franklin BS. Bertheloot D, et al. Among authors: franklin bs. EMBO Mol Med. 2022 Jun 8;14(6):e15415. doi: 10.15252/emmm.202115415. Epub 2022 Apr 19. EMBO Mol Med. 2022. PMID: 35438238 Free PMC article.
MyD88-dependent activation of dendritic cells and CD4(+) T lymphocytes mediates symptoms, but is not required for the immunological control of parasites during rodent malaria.
Franklin BS, Rodrigues SO, Antonelli LR, Oliveira RV, Goncalves AM, Sales-Junior PA, Valente EP, Alvarez-Leite JI, Ropert C, Golenbock DT, Gazzinelli RT. Franklin BS, et al. Microbes Infect. 2007 Jun;9(7):881-90. doi: 10.1016/j.micinf.2007.03.007. Epub 2007 Mar 21. Microbes Infect. 2007. PMID: 17537666 Free article.
Regulation of Innate Immune Responses by Platelets.
Ribeiro LS, Migliari Branco L, Franklin BS. Ribeiro LS, et al. Among authors: franklin bs. Front Immunol. 2019 Jun 11;10:1320. doi: 10.3389/fimmu.2019.01320. eCollection 2019. Front Immunol. 2019. PMID: 31244858 Free PMC article. Review.
47 results