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The P2X7 Receptor in Microglial Cells Modulates the Endolysosomal Axis, Autophagy, and Phagocytosis.
Front Cell Neurosci. 2021 Mar 15;15:645244. doi: 10.3389/fncel.2021.645244. eCollection 2021.
Front Cell Neurosci. 2021.
PMID: 33790743
Free PMC article.
Polarized Cytokine Release Triggered by P2X7 Receptor from Retinal Pigmented Epithelial Cells Dependent on Calcium Influx.
Shao X, Guha S, Lu W, Campagno KE, Beckel JM, Mills JA, Yang W, Mitchell CH.
Shao X, et al. Among authors: campagno ke.
Cells. 2020 Nov 24;9(12):2537. doi: 10.3390/cells9122537.
Cells. 2020.
PMID: 33255431
Free PMC article.
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Rapid morphologic changes to microglial cells and upregulation of mixed microglial activation state markers induced by P2X7 receptor stimulation and increased intraocular pressure.
Campagno KE, Lu W, Jassim AH, Albalawi F, Cenaj A, Tso HY, Clark SP, Sripinun P, Gómez NM, Mitchell CH.
Campagno KE, et al.
J Neuroinflammation. 2021 Sep 20;18(1):217. doi: 10.1186/s12974-021-02251-7.
J Neuroinflammation. 2021.
PMID: 34544431
Free PMC article.
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Robust lysosomal calcium signaling through channel TRPML1 is impaired by lysosomal lipid accumulation.
Gómez NM, Lu W, Lim JC, Kiselyov K, Campagno KE, Grishchuk Y, Slaugenhaupt SA, Pfeffer BA, Fliesler SJ, Mitchell CH.
Gómez NM, et al. Among authors: campagno ke.
FASEB J. 2018 Feb;32(2):782-794. doi: 10.1096/fj.201700220RR. Epub 2018 Jan 4.
FASEB J. 2018.
PMID: 29030399
Free PMC article.
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Stimulation of TLR3 triggers release of lysosomal ATP in astrocytes and epithelial cells that requires TRPML1 channels.
Beckel JM, Gómez NM, Lu W, Campagno KE, Nabet B, Albalawi F, Lim JC, Boesze-Battaglia K, Mitchell CH.
Beckel JM, et al. Among authors: campagno ke.
Sci Rep. 2018 Apr 10;8(1):5726. doi: 10.1038/s41598-018-23877-3.
Sci Rep. 2018.
PMID: 29636491
Free PMC article.
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The P2Y12 Receptor Antagonist Ticagrelor Reduces Lysosomal pH and Autofluorescence in Retinal Pigmented Epithelial Cells From the ABCA4-/- Mouse Model of Retinal Degeneration.
Lu W, Gómez NM, Lim JC, Guha S, O'Brien-Jenkins A, Coffey EE, Campagno KE, McCaughey SA, Laties AM, Carlsson LG, Mitchell CH.
Lu W, et al. Among authors: campagno ke.
Front Pharmacol. 2018 Apr 19;9:242. doi: 10.3389/fphar.2018.00242. eCollection 2018.
Front Pharmacol. 2018.
PMID: 29725296
Free PMC article.
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Oral Delivery of the P2Y12 Receptor Antagonist Ticagrelor Prevents Loss of Photoreceptors in an ABCA4-/- Mouse Model of Retinal Degeneration.
Lu W, Campagno KE, Tso HY, Cenaj A, Laties AM, Carlsson LG, Mitchell CH.
Lu W, et al. Among authors: campagno ke.
Invest Ophthalmol Vis Sci. 2019 Jul 1;60(8):3046-3053. doi: 10.1167/iovs.19-27241.
Invest Ophthalmol Vis Sci. 2019.
PMID: 31319418
Free PMC article.
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