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Meningeal inflammation in multiple sclerosis induces phenotypic changes in cortical microglia that differentially associate with neurodegeneration.
van Olst L, Rodriguez-Mogeda C, Picon C, Kiljan S, James RE, Kamermans A, van der Pol SMA, Knoop L, Michailidou I, Drost E, Franssen M, Schenk GJ, Geurts JJG, Amor S, Mazarakis ND, van Horssen J, de Vries HE, Reynolds R, Witte ME. van Olst L, et al. Acta Neuropathol. 2021 Jun;141(6):881-899. doi: 10.1007/s00401-021-02293-4. Epub 2021 Mar 29. Acta Neuropathol. 2021. PMID: 33779783 Free PMC article.
Microglial activation arises after aggregation of phosphorylated-tau in a neuron-specific P301S tauopathy mouse model.
van Olst L, Verhaege D, Franssen M, Kamermans A, Roucourt B, Carmans S, Ytebrouck E, van der Pol SMA, Wever D, Popovic M, Vandenbroucke RE, Sobrino T, Schouten M, de Vries HE. van Olst L, et al. Neurobiol Aging. 2020 May;89:89-98. doi: 10.1016/j.neurobiolaging.2020.01.003. Epub 2020 Jan 10. Neurobiol Aging. 2020. PMID: 32008854 Free article.
Crossing borders in Alzheimer's disease: A T cell's perspective.
van Olst L, Coenen L, Nieuwland JM, Rodriguez-Mogeda C, de Wit NM, Kamermans A, Middeldorp J, de Vries HE. van Olst L, et al. Adv Drug Deliv Rev. 2022 Sep;188:114398. doi: 10.1016/j.addr.2022.114398. Epub 2022 Jun 30. Adv Drug Deliv Rev. 2022. PMID: 35780907 Free article. Review.
Adaptive immune changes associate with clinical progression of Alzheimer's disease.
van Olst L, Kamermans A, Halters S, van der Pol SMA, Rodriguez E, Verberk IMW, Verberk SGS, Wessels DWR, Rodriguez-Mogeda C, Verhoeff J, Wouters D, Van den Bossche J, Garcia-Vallejo JJ, Lemstra AW, Witte ME, van der Flier WM, Teunissen CE, de Vries HE. van Olst L, et al. Mol Neurodegener. 2024 Apr 24;19(1):38. doi: 10.1186/s13024-024-00726-8. Mol Neurodegener. 2024. PMID: 38658964 Free PMC article.
Cerebrospinal fluid immune dysregulation during healthy brain aging and cognitive impairment.
Piehl N, van Olst L, Ramakrishnan A, Teregulova V, Simonton B, Zhang Z, Tapp E, Channappa D, Oh H, Losada PM, Rutledge J, Trelle AN, Mormino EC, Elahi F, Galasko DR, Henderson VW, Wagner AD, Wyss-Coray T, Gate D. Piehl N, et al. Among authors: van olst l. Cell. 2022 Dec 22;185(26):5028-5039.e13. doi: 10.1016/j.cell.2022.11.019. Epub 2022 Dec 13. Cell. 2022. PMID: 36516855 Free PMC article.
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