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DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation.
Hollingsworth LR, Sharif H, Griswold AR, Fontana P, Mintseris J, Dagbay KB, Paulo JA, Gygi SP, Bachovchin DA, Wu H. Hollingsworth LR, et al. Among authors: wu h. Nature. 2021 Apr;592(7856):778-783. doi: 10.1038/s41586-021-03350-4. Epub 2021 Mar 17. Nature. 2021. PMID: 33731932 Free PMC article.
Distinct molecular mechanism for initiating TRAF6 signalling.
Ye H, Arron JR, Lamothe B, Cirilli M, Kobayashi T, Shevde NK, Segal D, Dzivenu OK, Vologodskaia M, Yim M, Du K, Singh S, Pike JW, Darnay BG, Choi Y, Wu H. Ye H, et al. Among authors: wu h. Nature. 2002 Jul 25;418(6896):443-7. doi: 10.1038/nature00888. Nature. 2002. PMID: 12140561
Crystal structure of inhibitor of κB kinase β.
Xu G, Lo YC, Li Q, Napolitano G, Wu X, Jiang X, Dreano M, Karin M, Wu H. Xu G, et al. Among authors: wu x, wu h. Nature. 2011 Apr 21;472(7343):325-30. doi: 10.1038/nature09853. Epub 2011 Mar 20. Nature. 2011. PMID: 21423167 Free PMC article.
Structural mechanisms of inflammasome assembly.
Lu A, Wu H. Lu A, et al. Among authors: wu h. FEBS J. 2015 Feb;282(3):435-44. doi: 10.1111/febs.13133. Epub 2014 Nov 21. FEBS J. 2015. PMID: 25354325 Free PMC article. Review.
The ubiquitin-modifying enzyme A20 restricts ubiquitination of the kinase RIPK3 and protects cells from necroptosis.
Onizawa M, Oshima S, Schulze-Topphoff U, Oses-Prieto JA, Lu T, Tavares R, Prodhomme T, Duong B, Whang MI, Advincula R, Agelidis A, Barrera J, Wu H, Burlingame A, Malynn BA, Zamvil SS, Ma A. Onizawa M, et al. Among authors: wu h. Nat Immunol. 2015 Jun;16(6):618-27. doi: 10.1038/ni.3172. Epub 2015 May 4. Nat Immunol. 2015. PMID: 25939025 Free PMC article.
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