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Multifunctional opioid receptor agonism and antagonism by a novel macrocyclic tetrapeptide prevents reinstatement of morphine-seeking behaviour.
Brice-Tutt AC, Wilson LL, Eans SO, Stacy HM, Simons CA, Simpson GG, Coleman JS, Ferracane MJ, Aldrich JV, McLaughlin JP. Brice-Tutt AC, et al. Among authors: ferracane mj. Br J Pharmacol. 2020 Sep;177(18):4209-4222. doi: 10.1111/bph.15165. Epub 2020 Jul 16. Br J Pharmacol. 2020. PMID: 32562259 Free PMC article.
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins.
Malaker SA, Pedram K, Ferracane MJ, Bensing BA, Krishnan V, Pett C, Yu J, Woods EC, Kramer JR, Westerlind U, Dorigo O, Bertozzi CR. Malaker SA, et al. Among authors: ferracane mj. Proc Natl Acad Sci U S A. 2019 Apr 9;116(15):7278-7287. doi: 10.1073/pnas.1813020116. Epub 2019 Mar 25. Proc Natl Acad Sci U S A. 2019. PMID: 30910957 Free PMC article.
Design of a mucin-selective protease for targeted degradation of cancer-associated mucins.
Pedram K, Shon DJ, Tender GS, Mantuano NR, Northey JJ, Metcalf KJ, Wisnovsky SP, Riley NM, Forcina GC, Malaker SA, Kuo A, George BM, Miller CL, Casey KM, Vilches-Moure JG, Ferracane MJ, Weaver VM, Läubli H, Bertozzi CR. Pedram K, et al. Among authors: ferracane mj. Nat Biotechnol. 2024 Apr;42(4):597-607. doi: 10.1038/s41587-023-01840-6. Epub 2023 Aug 3. Nat Biotechnol. 2024. PMID: 37537499 Free PMC article.
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