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The Widely Used Antihelmintic Drug Albendazole is a Potent Inducer of Loss of Heterozygosity.
Will Castro LSEP, Pieters W, Alemdehy MF, Aslam MA, Buoninfante OA, Raaijmakers JA, Pilzecker B, van den Berk PCM, Te Riele H, Medema RH, Pedrosa RC, Jacobs H. Will Castro LSEP, et al. Among authors: te riele h. Front Pharmacol. 2021 Feb 18;12:596535. doi: 10.3389/fphar.2021.596535. eCollection 2021. Front Pharmacol. 2021. PMID: 33679394 Free PMC article.
Pro-mutagenic effects of the gut microbiota in a Lynch syndrome mouse model.
Pieters W, Hugenholtz F, Kos K, Cammeraat M, Moliej TC, Kaldenbach D, Klarenbeek S, Davids M, Drost L, de Konink C, Delzenne-Goette E, de Visser KE, Te Riele H. Pieters W, et al. Among authors: te riele h. Gut Microbes. 2022 Jan-Dec;14(1):2035660. doi: 10.1080/19490976.2022.2035660. Gut Microbes. 2022. PMID: 35188867 Free PMC article.
Unexpected moves: a conformational change in MutSα enables high-affinity DNA mismatch binding.
Bruekner SR, Pieters W, Fish A, Liaci AM, Scheffers S, Rayner E, Kaldenbach D, Drost L, Dekker M, van Hees-Stuivenberg S, Delzenne-Goette E, de Konink C, Houlleberghs H, Dubbink HJ, AlSaegh A, de Wind N, Förster F, Te Riele H, Sixma TK. Bruekner SR, et al. Among authors: te riele h. Nucleic Acids Res. 2023 Feb 22;51(3):1173-1188. doi: 10.1093/nar/gkad015. Nucleic Acids Res. 2023. PMID: 36715327 Free PMC article.
Paradoxical activation of oncogenic signaling as a cancer treatment strategy.
Dias MH, Friskes A, Wang S, Fernandes Neto JM, van Gemert F, Mourragui S, Papagianni C, Kuiken HJ, Mainardi S, Alvarez-Villanueva D, Lieftink C, Morris B, Dekker A, van Dijk E, Wilms LHS, da Silva MS, Jansen RA, Mulero-Sanchez A, Malzer E, Vidal A, Santos C, Salazar R, Wailemann RAM, Torres TEP, De Conti G, Raaijmakers JA, Snaebjornsson P, Yuan S, Qin W, Kovach JS, Armelin HA, Te Riele H, van Oudernaarden A, Jin H, Beijersbergen RL, Villanueva A, Medema RH, Bernards R. Dias MH, et al. Among authors: te riele h. Cancer Discov. 2024 Mar 27. doi: 10.1158/2159-8290.CD-23-0216. Online ahead of print. Cancer Discov. 2024. PMID: 38533987
126 results