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Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology.
Neuron. 2021 Apr 21;109(8):1283-1301.e6. doi: 10.1016/j.neuron.2021.02.010. Epub 2021 Mar 5.
Neuron. 2021.
PMID: 33675684
Free article.
TREM2-independent oligodendrocyte, astrocyte, and T cell responses to tau and amyloid pathology in mouse models of Alzheimer disease.
Lee SH, Rezzonico MG, Friedman BA, Huntley MH, Meilandt WJ, Pandey S, Chen YJ, Easton A, Modrusan Z, Hansen DV, Sheng M, Bohlen CJ.
Lee SH, et al. Among authors: rezzonico mg.
Cell Rep. 2021 Dec 28;37(13):110158. doi: 10.1016/j.celrep.2021.110158.
Cell Rep. 2021.
PMID: 34965428
Free article.
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Disease-associated oligodendrocyte responses across neurodegenerative diseases.
Pandey S, Shen K, Lee SH, Shen YA, Wang Y, Otero-García M, Kotova N, Vito ST, Laufer BI, Newton DF, Rezzonico MG, Hanson JE, Kaminker JS, Bohlen CJ, Yuen TJ, Friedman BA.
Pandey S, et al. Among authors: rezzonico mg.
Cell Rep. 2022 Aug 23;40(8):111189. doi: 10.1016/j.celrep.2022.111189.
Cell Rep. 2022.
PMID: 36001972
Free article.
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Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer's disease mouse models.
Dejanovic B, Wu T, Tsai MC, Graykowski D, Gandham VD, Rose CM, Bakalarski CE, Ngu H, Wang Y, Pandey S, Rezzonico MG, Friedman BA, Edmonds R, De Mazière A, Rakosi-Schmidt R, Singh T, Klumperman J, Foreman O, Chang MC, Xie L, Sheng M, Hanson JE.
Dejanovic B, et al. Among authors: rezzonico mg.
Nat Aging. 2022 Sep;2(9):837-850. doi: 10.1038/s43587-022-00281-1. Epub 2022 Sep 20.
Nat Aging. 2022.
PMID: 37118504
Free PMC article.
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TPL2 kinase activity regulates microglial inflammatory responses and promotes neurodegeneration in tauopathy mice.
Wang Y, Wu T, Tsai MC, Rezzonico MG, Abdel-Haleem AM, Xie L, Gandham VD, Ngu H, Stark K, Glock C, Xu D, Foreman O, Friedman BA, Sheng M, Hanson JE.
Wang Y, et al. Among authors: rezzonico mg.
Elife. 2023 Aug 9;12:e83451. doi: 10.7554/eLife.83451.
Elife. 2023.
PMID: 37555828
Free PMC article.
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Neutral or detrimental effects of TREM2 agonist antibodies in preclinical models of Alzheimer's Disease and Multiple Sclerosis.
Etxeberria A, Shen YA, Vito S, Silverman S, Imperio J, Lalehzadeh G, Soung A, Du C, Xie L, Choy MK, Hsiao YC, Ngu H, Cho CH, Ghosh S, Novikova G, Rezzonico MG, Leahey R, Weber M, Gogineni A, Elstrott J, Xiong M, Greene JJ, Stark KL, Chan P, Roth GA, Adrian M, Li Q, Choi M, Wong WR, Sandoval W, Foreman O, Nugent AA, Friedman BA, Sadekar S, Hötzel I, Hansen DV, Chih B, Yuen TJ, Weimer RM, Easton A, Meilandt WJ, Bohlen CJ.
Etxeberria A, et al. Among authors: rezzonico mg.
J Neurosci. 2024 Jun 3:e2347232024. doi: 10.1523/JNEUROSCI.2347-23.2024. Online ahead of print.
J Neurosci. 2024.
PMID: 38830764
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