Wipf P - Search Results

1

Endothelial Iron Homeostasis Regulates Blood-Brain Barrier Integrity via the HIF2α-Ve-Cadherin Pathway.

Rand D, Ravid O, Atrakchi D, Israelov H, Bresler Y, Shemesh C, Omesi L, Liraz-Zaltsman S, Gosselet F, Maskrey TS, Beeri MS, Wipf P, Cooper I. Rand D, et al. Among authors: wipf p. Pharmaceutics. 2021 Feb 28;13(3):311. doi: 10.3390/pharmaceutics13030311. Pharmaceutics. 2021. PMID: 33670876 Free PMC article.

2

A High-Content Screen Reveals New Small-Molecule Enhancers of Ras/Mapk Signaling as Probes for Zebrafish Heart Development.

Saydmohammed M, Vollmer LL, Onuoha EO, Maskrey TS, Gibson G, Watkins SC, Wipf P, Vogt A, Tsang M. Saydmohammed M, et al. Among authors: wipf p. Molecules. 2018 Jul 11;23(7):1691. doi: 10.3390/molecules23071691. Molecules. 2018. PMID: 29997348 Free PMC article.

3

Synthesis and Evaluation of a Mitochondria-Targeting Poly(ADP-ribose) Polymerase-1 Inhibitor.

Krainz T, Lamade AM, Du L, Maskrey TS, Calderon MJ, Watkins SC, Epperly MW, Greenberger JS, Bayır H, Wipf P, Clark RSB. Krainz T, et al. Among authors: wipf p. ACS Chem Biol. 2018 Oct 19;13(10):2868-2879. doi: 10.1021/acschembio.8b00423. Epub 2018 Sep 14. ACS Chem Biol. 2018. PMID: 30184433 Free PMC article.

4

A Five-Component Biginelli-Diels-Alder Cascade Reaction.

Maskrey TS, Frischling MC, Rice ML, Wipf P. Maskrey TS, et al. Among authors: wipf p. Front Chem. 2018 Aug 24;6:376. doi: 10.3389/fchem.2018.00376. eCollection 2018. Front Chem. 2018. PMID: 30211156 Free PMC article.

5

Co(II)-salen catalyzed stereoselective cyclopropanation of fluorinated styrenes.

Tai S, Maskrey TS, Nyalapatla PR, Wipf P. Tai S, et al. Among authors: wipf p. Chirality. 2019 Dec;31(12):1014-1027. doi: 10.1002/chir.23144. Epub 2019 Nov 3. Chirality. 2019. PMID: 31680333

6

Structure of the Complex of an Iminopyridinedione Protein Tyrosine Phosphatase 4A3 Phosphatase Inhibitor with Human Serum Albumin.

Czub MP, Boulton AM, Rastelli EJ, Tasker NR, Maskrey TS, Blanco IK, McQueeney KE, Bushweller JH, Minor W, Wipf P, Sharlow ER, Lazo JS. Czub MP, et al. Among authors: wipf p. Mol Pharmacol. 2020 Dec;98(6):648-657. doi: 10.1124/molpharm.120.000131. Epub 2020 Sep 25. Mol Pharmacol. 2020. PMID: 32978326 Free PMC article.

7

Synthesis and Optimization of Nitroxide-Based Inhibitors of Ferroptotic Cell Death in Cancer Cells and Macrophages.

Charaschanya M, Maskrey TS, LaPorte MG, Janjic JM, Wipf P. Charaschanya M, et al. Among authors: wipf p. ACS Med Chem Lett. 2022 Feb 4;13(3):403-408. doi: 10.1021/acsmedchemlett.1c00561. eCollection 2022 Mar 10. ACS Med Chem Lett. 2022. PMID: 35300093 Free PMC article.

8

Design, Synthesis, and Biological Evaluation of PKD Inhibitors.

George KM, Frantz MC, Bravo-Altamirano K, Lavalle CR, Tandon M, Leimgruber S, Sharlow ER, Lazo JS, Wang QJ, Wipf P. George KM, et al. Among authors: wipf p. Pharmaceutics. 2011;3(2):186-228. doi: 10.3390/pharmaceutics3020186. Pharmaceutics. 2011. PMID: 22267986 Free PMC article.

9

A Novel Small Molecule Targets Androgen Receptor and Its Splice Variants in Castration-Resistant Prostate Cancer.

Yang Z, Wang D, Johnson JK, Pascal LE, Takubo K, Avula R, Chakka AB, Zhou J, Chen W, Zhong M, Song Q, Ding H, Wu Z, Chandran UR, Maskrey TS, Nelson JB, Wipf P, Wang Z. Yang Z, et al. Among authors: wipf p. Mol Cancer Ther. 2020 Jan;19(1):75-88. doi: 10.1158/1535-7163.MCT-19-0489. Epub 2019 Sep 25. Mol Cancer Ther. 2020. PMID: 31554654 Free PMC article.

10

Binding Site Interactions of Modulators of Breast Cancer Resistance Protein, Multidrug Resistance-Associated Protein 2, and P-Glycoprotein Activity.

Deng F, Ghemtio L, Grazhdankin E, Wipf P, Xhaard H, Kidron H. Deng F, et al. Among authors: wipf p. Mol Pharm. 2020 Jul 6;17(7):2398-2410. doi: 10.1021/acs.molpharmaceut.0c00155. Epub 2020 Jun 18. Mol Pharm. 2020. PMID: 32496785 Free PMC article.

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