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Drimane Derivatives as the First Examples of Covalent BH3 Mimetics that Target MCL-1.
Daressy F, Malard F, Seguy L, Guérineau V, Apel C, Dumontet V, Robert A, Groo AC, Litaudon M, Bignon J, Desrat S, Malzert-Fréon A, Wiels J, Lescop E, Roussi F. Daressy F, et al. Among authors: malard f. ChemMedChem. 2021 Jun 7;16(11):1788-1797. doi: 10.1002/cmdc.202100011. Epub 2021 Mar 23. ChemMedChem. 2021. PMID: 33665938
Less effective selection leads to larger genomes.
Lefébure T, Morvan C, Malard F, François C, Konecny-Dupré L, Guéguen L, Weiss-Gayet M, Seguin-Orlando A, Ermini L, Sarkissian C, Charrier NP, Eme D, Mermillod-Blondin F, Duret L, Vieira C, Orlando L, Douady CJ. Lefébure T, et al. Among authors: malard f. Genome Res. 2017 Jun;27(6):1016-1028. doi: 10.1101/gr.212589.116. Epub 2017 Apr 19. Genome Res. 2017. PMID: 28424354 Free PMC article.
Bedrock radioactivity influences the rate and spectrum of mutation.
Saclier N, Chardon P, Malard F, Konecny-Dupré L, Eme D, Bellec A, Breton V, Duret L, Lefebure T, Douady CJ. Saclier N, et al. Among authors: malard f. Elife. 2020 Nov 30;9:e56830. doi: 10.7554/eLife.56830. Elife. 2020. PMID: 33252037 Free PMC article.
202 results