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Polygenic hazard score is associated with prostate cancer in multi-ethnic populations.
Huynh-Le MP, Fan CC, Karunamuni R, Thompson WK, Martinez ME, Eeles RA, Kote-Jarai Z, Muir K, Schleutker J, Pashayan N, Batra J, Grönberg H, Neal DE, Donovan JL, Hamdy FC, Martin RM, Nielsen SF, Nordestgaard BG, Wiklund F, Tangen CM, Giles GG, Wolk A, Albanes D, Travis RC, Blot WJ, Zheng W, Sanderson M, Stanford JL, Mucci LA, West CML, Kibel AS, Cussenot O, Berndt SI, Koutros S, Sørensen KD, Cybulski C, Grindedal EM, Menegaux F, Khaw KT, Park JY, Ingles SA, Maier C, Hamilton RJ, Thibodeau SN, Rosenstein BS, Lu YJ, Watya S, Vega A, Kogevinas M, Penney KL, Huff C, Teixeira MR, Multigner L, Leach RJ, Cannon-Albright L, Brenner H, John EM, Kaneva R, Logothetis CJ, Neuhausen SL, De Ruyck K, Pandha H, Razack A, Newcomb LF, Fowke JH, Gamulin M, Usmani N, Claessens F, Gago-Dominguez M, Townsend PA, Bush WS, Roobol MJ, Parent MÉ, Hu JJ, Mills IG, Andreassen OA, Dale AM, Seibert TM; UKGPCS collaborators; APCB (Australian Prostate Cancer BioResource); NC-LA PCaP Investigators; IMPACT Study Steering Committee and Collaborators; Canary PASS Investigators; Profile Study Steering Committee; PRACTICAL Consortium. Huynh-Le MP, et al. Among authors: ingles sa. Nat Commun. 2021 Feb 23;12(1):1236. doi: 10.1038/s41467-021-21287-0. Nat Commun. 2021. PMID: 33623038 Free PMC article.
Admixture mapping identifies 8q24 as a prostate cancer risk locus in African-American men.
Freedman ML, Haiman CA, Patterson N, McDonald GJ, Tandon A, Waliszewska A, Penney K, Steen RG, Ardlie K, John EM, Oakley-Girvan I, Whittemore AS, Cooney KA, Ingles SA, Altshuler D, Henderson BE, Reich D. Freedman ML, et al. Among authors: ingles sa. Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):14068-73. doi: 10.1073/pnas.0605832103. Epub 2006 Aug 31. Proc Natl Acad Sci U S A. 2006. PMID: 16945910 Free PMC article.
Multiple regions within 8q24 independently affect risk for prostate cancer.
Haiman CA, Patterson N, Freedman ML, Myers SR, Pike MC, Waliszewska A, Neubauer J, Tandon A, Schirmer C, McDonald GJ, Greenway SC, Stram DO, Le Marchand L, Kolonel LN, Frasco M, Wong D, Pooler LC, Ardlie K, Oakley-Girvan I, Whittemore AS, Cooney KA, John EM, Ingles SA, Altshuler D, Henderson BE, Reich D. Haiman CA, et al. Among authors: ingles sa. Nat Genet. 2007 May;39(5):638-44. doi: 10.1038/ng2015. Epub 2007 Apr 1. Nat Genet. 2007. PMID: 17401364 Free PMC article.
199 results