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A small-molecule cell-based screen led to the identification of biphenylimidazoazines with highly potent and broad-spectrum anti-apicomplexan activity.
Moine E, Denevault-Sabourin C, Debierre-Grockiego F, Silpa L, Gorgette O, Barale JC, Jacquiet P, Brossier F, Gueiffier A, Dimier-Poisson I, Enguehard-Gueiffier C. Moine E, et al. Eur J Med Chem. 2015 Jan 7;89:386-400. doi: 10.1016/j.ejmech.2014.10.057. Epub 2014 Oct 22. Eur J Med Chem. 2015. PMID: 25462254
Imidazo[1,2-b]pyridazines targeting Toxoplasma gondii calcium-dependent protein kinase 1 decrease the parasite burden in mice with acute toxoplasmosis.
Moine E, Moiré N, Dimier-Poisson I, Brunet K, Couet W, Colas C, Van Langendonck N, Enguehard-Gueiffier C, Gueiffier A, Héraut B, Denevault-Sabourin C, Debierre-Grockiego F. Moine E, et al. Int J Parasitol. 2018 Jun;48(7):561-568. doi: 10.1016/j.ijpara.2017.12.006. Epub 2018 Mar 7. Int J Parasitol. 2018. PMID: 29524527
Recent Advances in the Roles of Neutrophils in Toxoplasmosis.
Debierre-Grockiego F, Moiré N, Torres Arias M, Dimier-Poisson I. Debierre-Grockiego F, et al. Trends Parasitol. 2020 Dec;36(12):956-958. doi: 10.1016/j.pt.2020.08.007. Epub 2020 Sep 17. Trends Parasitol. 2020. PMID: 32952059 Review.
Neospora caninum: a new class of biopharmaceuticals in the therapeutic arsenal against cancer.
Lantier L, Poupée-Beaugé A, di Tommaso A, Ducournau C, Epardaud M, Lakhrif Z, Germon S, Debierre-Grockiego F, Mévélec MN, Battistoni A, Coënon L, Deluce-Kakwata-Nkor N, Velge-Roussel F, Beauvillain C, Baranek T, Lee GS, Kervarrec T, Touzé A, Moiré N, Dimier-Poisson I. Lantier L, et al. J Immunother Cancer. 2020 Nov;8(2):e001242. doi: 10.1136/jitc-2020-001242. J Immunother Cancer. 2020. PMID: 33257408 Free PMC article.
78 results