Fu Y - Search Results

1

CD4+ T cells from children with active juvenile idiopathic arthritis show altered chromatin features associated with transcriptional abnormalities.

Tarbell E, Jiang K, Hennon TR, Holmes L, Williams S, Fu Y, Gaffney PM, Liu T, Jarvis JN. Tarbell E, et al. Among authors: fu y. Sci Rep. 2021 Feb 17;11(1):4011. doi: 10.1038/s41598-021-82989-5. Sci Rep. 2021. PMID: 33597588 Free PMC article.

2

Enhancer histone-QTLs are enriched on autoimmune risk haplotypes and influence gene expression within chromatin networks.

Pelikan RC, Kelly JA, Fu Y, Lareau CA, Tessneer KL, Wiley GB, Wiley MM, Glenn SB, Harley JB, Guthridge JM, James JA, Aryee MJ, Montgomery C, Gaffney PM. Pelikan RC, et al. Among authors: fu y. Nat Commun. 2018 Jul 25;9(1):2905. doi: 10.1038/s41467-018-05328-9. Nat Commun. 2018. PMID: 30046115 Free PMC article.

3

From association to mechanism in complex disease genetics: the role of the 3D genome.

Fu Y, Tessneer KL, Li C, Gaffney PM. Fu Y, et al. Arthritis Res Ther. 2018 Sep 29;20(1):216. doi: 10.1186/s13075-018-1721-x. Arthritis Res Ther. 2018. PMID: 30268153 Free PMC article. Review.

4

Role of Systemic Lupus Erythematosus Risk Variants With Opposing Functional Effects as a Driver of Hypomorphic Expression of TNIP1 and Other Genes Within a Three-Dimensional Chromatin Network.

Pasula S, Tessneer KL, Fu Y, Gopalakrishnan J, Pelikan RC, Kelly JA, Wiley GB, Wiley MM, Gaffney PM. Pasula S, et al. Among authors: fu y. Arthritis Rheumatol. 2020 May;72(5):780-790. doi: 10.1002/art.41188. Epub 2020 Mar 30. Arthritis Rheumatol. 2020. PMID: 31804013 Free PMC article.

5

Mapping DNA interaction landscapes in psoriasis susceptibility loci highlights KLF4 as a target gene in 9q31.

Ray-Jones H, Duffus K, McGovern A, Martin P, Shi C, Hankinson J, Gough O, Yarwood A, Morris AP, Adamson A, Taylor C, Ding J, Gaddi VP, Fu Y, Gaffney P, Orozco G, Warren RB, Eyre S. Ray-Jones H, et al. Among authors: fu y. BMC Biol. 2020 May 4;18(1):47. doi: 10.1186/s12915-020-00779-3. BMC Biol. 2020. PMID: 32366252 Free PMC article.

6

Chromatin Looping Links Target Genes with Genetic Risk Loci for Dermatological Traits.

Shi C, Ray-Jones H, Ding J, Duffus K, Fu Y, Gaddi VP, Gough O, Hankinson J, Martin P, McGovern A, Yarwood A, Gaffney P, Eyre S, Rattray M, Warren RB, Orozco G. Shi C, et al. Among authors: fu y. J Invest Dermatol. 2021 Aug;141(8):1975-1984. doi: 10.1016/j.jid.2021.01.015. Epub 2021 Feb 17. J Invest Dermatol. 2021. PMID: 33607115 Free PMC article.

7

Variants on the UBE2L3/YDJC Autoimmune Disease Risk Haplotype Increase UBE2L3 Expression by Modulating CCCTC-Binding Factor and YY1 Binding.

Gopalakrishnan J, Tessneer KL, Fu Y, Pasula S, Pelikan RC, Kelly JA, Wiley GB, Gaffney PM. Gopalakrishnan J, et al. Among authors: fu y. Arthritis Rheumatol. 2022 Jan;74(1):163-173. doi: 10.1002/art.41925. Epub 2021 Dec 13. Arthritis Rheumatol. 2022. PMID: 34279042 Free PMC article.

8

Systemic lupus erythematosus variants modulate the function of an enhancer upstream of TNFAIP3.

Pasula S, Gopalakrishnan J, Fu Y, Tessneer KL, Wiley MM, Pelikan RC, Kelly JA, Gaffney PM. Pasula S, et al. Among authors: fu y. Front Genet. 2022 Sep 19;13:1011965. doi: 10.3389/fgene.2022.1011965. eCollection 2022. Front Genet. 2022. PMID: 36199584 Free PMC article.

9

Massively Parallel Reporter Assay Confirms Regulatory Potential of hQTLs and Reveals Important Variants in Lupus and Other Autoimmune Diseases.

Fu Y, Kelly JA, Gopalakrishnan J, Pelikan RC, Tessneer KL, Pasula S, Grundahl K, Murphy DA, Gaffney PM. Fu Y, et al. bioRxiv [Preprint]. 2023 Aug 18:2023.08.17.553722. doi: 10.1101/2023.08.17.553722. bioRxiv. 2023. PMID: 37645944 Free PMC article. Updated. Preprint.

10

Comparison of the three-dimensional chromatin structures of adolescent and adult peripheral blood B cells: implications for the study of pediatric autoimmune diseases.

Jiang K, Fu Y, Kelly JA, Gaffney PM, Holmes LC, Jarvis JN. Jiang K, et al. Among authors: fu y. bioRxiv [Preprint]. 2023 Sep 14:2023.09.11.557171. doi: 10.1101/2023.09.11.557171. bioRxiv. 2023. PMID: 37745336 Free PMC article. Preprint.

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