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Mutations that collaborate with IL-7Ra signaling pathways to drive ALL.
Rodrigues GOL, Cramer SD, Winer HY, Hixon JA, Li W, Yunes JA, Durum SK. Rodrigues GOL, et al. Among authors: yunes ja. Adv Biol Regul. 2021 May;80:100788. doi: 10.1016/j.jbior.2021.100788. Epub 2021 Jan 21. Adv Biol Regul. 2021. PMID: 33578108 Review.
Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia.
Zenatti PP, Ribeiro D, Li W, Zuurbier L, Silva MC, Paganin M, Tritapoe J, Hixon JA, Silveira AB, Cardoso BA, Sarmento LM, Correia N, Toribio ML, Kobarg J, Horstmann M, Pieters R, Brandalise SR, Ferrando AA, Meijerink JP, Durum SK, Yunes JA, Barata JT. Zenatti PP, et al. Among authors: yunes ja. Nat Genet. 2011 Sep 4;43(10):932-9. doi: 10.1038/ng.924. Nat Genet. 2011. PMID: 21892159 Free PMC article.
Physiologic IGFBP7 levels prolong IGF1R activation in acute lymphoblastic leukemia.
Artico LL, Laranjeira ABA, Campos LW, Corrêa JR, Zenatti PP, Carvalheira JBC, Brambilla SR, Nowill AE, Brandalise SR, Yunes JA. Artico LL, et al. Among authors: yunes ja. Blood Adv. 2021 Sep 28;5(18):3633-3646. doi: 10.1182/bloodadvances.2020003627. Blood Adv. 2021. PMID: 34438446 Free PMC article.
Deleterious and Oncogenic Mutations in the IL7RA.
Campos LW, Pissinato LG, Yunes JA. Campos LW, et al. Among authors: yunes ja. Cancers (Basel). 2019 Dec 5;11(12):1952. doi: 10.3390/cancers11121952. Cancers (Basel). 2019. PMID: 31817502 Free PMC article. Review.
IKAROS and CK2 regulate expression of BCL-XL and chemosensitivity in high-risk B-cell acute lymphoblastic leukemia.
Song C, Ge Z, Ding Y, Tan BH, Desai D, Gowda K, Amin S, Gowda R, Robertson GP, Yue F, Huang S, Spiegelman V, Payne JL, Reeves ME, Gurel Z, Iyer S, Dhanyamraju PK, Xiang M, Kawasawa YI, Cury NM, Yunes JA, McGrath M, Schramm J, Su R, Yang Y, Zhao Z, Lyu X, Muschen M, Payne KJ, Gowda C, Dovat S. Song C, et al. Among authors: yunes ja. Blood. 2020 Sep 24;136(13):1520-1534. doi: 10.1182/blood.2019002655. Blood. 2020. PMID: 32396934 Free PMC article.
Interleukin-7 receptor α mutational activation can initiate precursor B-cell acute lymphoblastic leukemia.
Almeida ARM, Neto JL, Cachucho A, Euzébio M, Meng X, Kim R, Fernandes MB, Raposo B, Oliveira ML, Ribeiro D, Fragoso R, Zenatti PP, Soares T, de Matos MR, Corrêa JR, Duque M, Roberts KG, Gu Z, Qu C, Pereira C, Pyne S, Pyne NJ, Barreto VM, Bernard-Pierrot I, Clappier E, Mullighan CG, Grosso AR, Yunes JA, Barata JT. Almeida ARM, et al. Among authors: yunes ja. Nat Commun. 2021 Dec 14;12(1):7268. doi: 10.1038/s41467-021-27197-5. Nat Commun. 2021. PMID: 34907175 Free PMC article.
135 results