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Sensing soluble uric acid by Naip1-Nlrp3 platform.
Braga TT, Davanso MR, Mendes D, de Souza TA, de Brito AF, Cruz MC, Hiyane MI, de Lima DS, Nunes V, de Fátima Giarola J, Souto DEP, Próchnicki T, Lauterbach M, Biscaia SMP, de Freitas RA, Curi R, Pontillo A, Latz E, Camara NOS. Braga TT, et al. Among authors: latz e. Cell Death Dis. 2021 Feb 5;12(2):158. doi: 10.1038/s41419-021-03445-w. Cell Death Dis. 2021. PMID: 33547278 Free PMC article.
Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.
Bauernfeind FG, Horvath G, Stutz A, Alnemri ES, MacDonald K, Speert D, Fernandes-Alnemri T, Wu J, Monks BG, Fitzgerald KA, Hornung V, Latz E. Bauernfeind FG, et al. Among authors: latz e. J Immunol. 2009 Jul 15;183(2):787-91. doi: 10.4049/jimmunol.0901363. Epub 2009 Jul 1. J Immunol. 2009. PMID: 19570822 Free PMC article.
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
Duewell P, Kono H, Rayner KJ, Sirois CM, Vladimer G, Bauernfeind FG, Abela GS, Franchi L, Nuñez G, Schnurr M, Espevik T, Lien E, Fitzgerald KA, Rock KL, Moore KJ, Wright SD, Hornung V, Latz E. Duewell P, et al. Among authors: latz e. Nature. 2010 Apr 29;464(7293):1357-61. doi: 10.1038/nature08938. Nature. 2010. PMID: 20428172 Free PMC article.
NLRP3 inflammasomes link inflammation and metabolic disease.
De Nardo D, Latz E. De Nardo D, et al. Among authors: latz e. Trends Immunol. 2011 Aug;32(8):373-9. doi: 10.1016/j.it.2011.05.004. Epub 2011 Jul 4. Trends Immunol. 2011. PMID: 21733753 Free PMC article. Review.
PKR stirs up inflammasomes.
Stunden HJ, Latz E. Stunden HJ, et al. Among authors: latz e. Cell Res. 2013 Feb;23(2):168-70. doi: 10.1038/cr.2012.125. Epub 2012 Sep 4. Cell Res. 2013. PMID: 22945351 Free PMC article.
NLRP3 protein deficiency exacerbates hyperoxia-induced lethality through Stat3 protein signaling independent of interleukin-1β.
Mizushina Y, Shirasuna K, Usui F, Karasawa T, Kawashima A, Kimura H, Kobayashi M, Komada T, Inoue Y, Mato N, Yamasawa H, Latz E, Iwakura Y, Kasahara T, Bando M, Sugiyama Y, Takahashi M. Mizushina Y, et al. Among authors: latz e. J Biol Chem. 2015 Feb 20;290(8):5065-5077. doi: 10.1074/jbc.M114.603217. Epub 2014 Dec 29. J Biol Chem. 2015. PMID: 25548278 Free PMC article.
329 results