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Thioredoxin-1 (Trx1) engineered mesenchymal stem cell therapy increased pro-angiogenic factors, reduced fibrosis and improved heart function in the infarcted rat myocardium.
Suresh SC, Selvaraju V, Thirunavukkarasu M, Goldman JW, Husain A, Alexander Palesty J, Sanchez JA, McFadden DW, Maulik N. Suresh SC, et al. Among authors: selvaraju v. Int J Cardiol. 2015 Dec 15;201:517-28. doi: 10.1016/j.ijcard.2015.08.117. Epub 2015 Aug 15. Int J Cardiol. 2015. PMID: 26322599
Disruption of VEGF Mediated Flk-1 Signaling Leads to a Gradual Loss of Vessel Health and Cardiac Function During Myocardial Infarction: Potential Therapy With Pellino-1.
Thirunavukkarasu M, Selvaraju V, Joshi M, Coca-Soliz V, Tapias L, Saad I, Fournier C, Husain A, Campbell J, Yee SP, Sanchez JA, Palesty JA, McFadden DW, Maulik N. Thirunavukkarasu M, et al. Among authors: selvaraju v. J Am Heart Assoc. 2018 Sep 18;7(18):e007601. doi: 10.1161/JAHA.117.007601. J Am Heart Assoc. 2018. PMID: 30371196 Free PMC article.
Simvastatin treatment inhibits hypoxia inducible factor 1-alpha-(HIF-1alpha)-prolyl-4-hydroxylase 3 (PHD-3) and increases angiogenesis after myocardial infarction in streptozotocin-induced diabetic rat.
Thirunavukkarasu M, Selvaraju V, Dunna NR, Foye JL, Joshi M, Otani H, Maulik N. Thirunavukkarasu M, et al. Among authors: selvaraju v. Int J Cardiol. 2013 Oct 3;168(3):2474-80. doi: 10.1016/j.ijcard.2013.03.005. Epub 2013 Apr 13. Int J Cardiol. 2013. PMID: 23590933
Deletion of prolyl hydroxylase domain proteins (PHD1, PHD3) stabilizes hypoxia inducible factor-1 alpha, promotes neovascularization, and improves perfusion in a murine model of hind-limb ischemia.
Rishi MT, Selvaraju V, Thirunavukkarasu M, Shaikh IA, Takeda K, Fong GH, Palesty JA, Sanchez JA, Maulik N. Rishi MT, et al. Among authors: selvaraju v. Microvasc Res. 2015 Jan;97:181-8. doi: 10.1016/j.mvr.2014.10.009. Epub 2014 Nov 3. Microvasc Res. 2015. PMID: 25446011
47 results