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The ubiquinone synthesis pathway is a promising drug target for Chagas disease.
Nara T, Nakagawa Y, Tsuganezawa K, Yuki H, Sekimata K, Koyama H, Ogawa N, Honma T, Shirouzu M, Fukami T, Matsuo Y, Inaoka DK, Kita K, Tanaka A. Nara T, et al. Among authors: nakagawa y. PLoS One. 2021 Feb 4;16(2):e0243855. doi: 10.1371/journal.pone.0243855. eCollection 2021. PLoS One. 2021. PMID: 33539347 Free PMC article.
Identification of small molecule inhibitors of human COQ7.
Tsuganezawa K, Sekimata K, Nakagawa Y, Utata R, Nakamura K, Ogawa N, Koyama H, Shirouzu M, Fukami T, Kita K, Tanaka A. Tsuganezawa K, et al. Among authors: nakagawa y. Bioorg Med Chem. 2020 Jan 1;28(1):115182. doi: 10.1016/j.bmc.2019.115182. Epub 2019 Nov 9. Bioorg Med Chem. 2020. PMID: 31753803
A novel Pim-1 kinase inhibitor targeting residues that bind the substrate peptide.
Tsuganezawa K, Watanabe H, Parker L, Yuki H, Taruya S, Nakagawa Y, Kamei D, Mori M, Ogawa N, Tomabechi Y, Handa N, Honma T, Yokoyama S, Kojima H, Okabe T, Nagano T, Tanaka A. Tsuganezawa K, et al. Among authors: nakagawa y. J Mol Biol. 2012 Mar 30;417(3):240-52. doi: 10.1016/j.jmb.2012.01.036. Epub 2012 Jan 30. J Mol Biol. 2012. PMID: 22306408
A fluorescent-based high-throughput screening assay for small molecules that inhibit the interaction of MdmX with p53.
Tsuganezawa K, Nakagawa Y, Kato M, Taruya S, Takahashi F, Endoh M, Utata R, Mori M, Ogawa N, Honma T, Yokoyama S, Hashizume Y, Aoki M, Kasai T, Kigawa T, Kojima H, Okabe T, Nagano T, Tanaka A. Tsuganezawa K, et al. Among authors: nakagawa y. J Biomol Screen. 2013 Feb;18(2):191-8. doi: 10.1177/1087057112460729. Epub 2012 Sep 18. J Biomol Screen. 2013. PMID: 22989451
Characterization of crystal water molecules in a high-affinity inhibitor and hematopoietic prostaglandin D synthase complex by interaction energy studies.
Takaya D, Inaka K, Omura A, Takenuki K, Kawanishi M, Yabuki Y, Nakagawa Y, Tsuganezawa K, Ogawa N, Watanabe C, Honma T, Aritake K, Urade Y, Shirouzu M, Tanaka A. Takaya D, et al. Among authors: nakagawa y. Bioorg Med Chem. 2018 Sep 1;26(16):4726-4734. doi: 10.1016/j.bmc.2018.08.014. Epub 2018 Aug 11. Bioorg Med Chem. 2018. PMID: 30121213
Thoracoscopic primary repair is useful for esophageal atresia with tracheoesophageal fistula in neonates with low body weight.
Gohda Y, Uchida H, Shirota C, Tainaka T, Sumida W, Makita S, Satomi M, Yasui A, Kanou Y, Nakagawa Y, Kato D, Maeda T, Guo Y, Liu J, Ishii H, Ota K, Hinoki A. Gohda Y, et al. Among authors: nakagawa y. Pediatr Surg Int. 2024 Jun 3;40(1):149. doi: 10.1007/s00383-024-05724-x. Pediatr Surg Int. 2024. PMID: 38829446 Free PMC article.
Safety of cannabidiol products as a social issue: A case series.
Maki Y, Tsuchiya A, Yamamoto R, Saito T, Morita S, Nakagawa Y. Maki Y, et al. Among authors: nakagawa y. Acute Med Surg. 2024 May 31;11(1):e965. doi: 10.1002/ams2.965. eCollection 2024 Jan-Dec. Acute Med Surg. 2024. PMID: 38828078 Free PMC article.
3,987 results